Interactor 1: KU70 (Q23976)
ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit dp70) (ATP-dependent helicase Irbp) (Inverted repeat-binding protein) (Yolk protein factor 1 subunit beta)
Gene: Irbp

Interactor 2: Q9I7M8 (Q9I7M8)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12)
Gene: Ku80

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22036573
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ku~Ku, Ku~Ku_N, Ku~Ku_C, Ku_C~Ku_N, Ku_C~Ku_PK_bind, Ku_N~Ku_N
Common GO terms GO:0000723 - telomere maintenance
GO:0003684 - damaged DNA binding
GO:0003690 - double-stranded DNA binding
GO:0005524 - ATP binding
GO:0006303 - double-strand break repair via nonhomologous end joining
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 631
Dm

1 699
+ Hs
+ Hs
+ At
+ Hs
+ Sp
+ Ce
+ Sc
+ Sc

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Last updated: 15 Jul 2024