Interactor 1: KU70 (Q23976)
ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit dp70) (ATP-dependent helicase Irbp) (Inverted repeat-binding protein) (Yolk protein factor 1 subunit beta)
Gene: Irbp

Interactor 2: Q9VYA5 (Q9VYA5)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: DNAlig4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22036573
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~Ku, BRCT_2~Ku_C, DNA_ligase_A_N~Ku_N
Common GO terms GO:0000723 - telomere maintenance
GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0006303 - double-strand break repair via nonhomologous end joining
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 631
Dm

1 918
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024