HitPredict

Interactor 1: RHOL (Q24192)
Ras-like GTP-binding protein RhoL
Gene: RHOL

Interactor 2: SYDE (Q9V9S7)
Rho GTPase-activating protein 100F (RhoGAP-100F) (Synapse defective protein 1 homolog) (Protein syd-1 homolog)
Gene: RhoGAP100F

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	29217522
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 190 Dm			1 1866
+	Dm
		819749 RAC2_DROME (10-190): 7.88e-89: 260: 50.26		SYDE_DROME (1-1866): 0: 1398: 100.00
+	Hs
		436289 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		MYO9B_HUMAN (352-1331): 5.46e-112: 399: 15.72
+	Hs
		436493 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		RHG39_HUMAN (263-1151): 1.35e-116: 399: 19.17
+	Hs
		892580 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG39_HUMAN (263-1151): 1.35e-116: 399: 19.17
+	Hs
		253333 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		SRGP2_HUMAN (761-1566): 1.67e-94: 334: 14.50
+	Hs
		892446 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		SYDE1_HUMAN (747-1197): 2.93e-96: 330: 33.41
+	Hs
		436136 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		BCR_HUMAN (786-1154): 2.6e-84: 306: 28.64
+	Hs
		64644 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		RHG32_HUMAN (894-1785): 1.58e-80: 298: 16.22
+	Hs
		64679 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG32_HUMAN (894-1785): 1.58e-80: 298: 16.22
+	Hs
		892620 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG35_HUMAN (567-1178): 1.91e-79: 293: 17.85
+	Hs
		436280 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		RHG05_HUMAN (620-1168): 3.49e-76: 282: 15.02
+	Hs
		892343 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG05_HUMAN (620-1168): 3.49e-76: 282: 15.02
+	Hs
		63072 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG42_HUMAN (767-1427): 1.34e-75: 273: 14.67
+	Hs
		436273 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		RHG01_HUMAN (909-1148): 1.78e-59: 214: 25.10
+	Hs
		892334 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG01_HUMAN (909-1148): 1.78e-59: 214: 25.10
+	Ce
		105260 CDC42_CAEEL (10-190): 2.13e-87: 256: 49.47		G5ECK6_CAEEL (942-1139): 6.16e-57: 208: 29.41
+	Ce
		983038 CDC42_CAEEL (10-190): 2.13e-87: 256: 49.47		Q965N4_CAEEL (943-1130): 5.38e-56: 203: 29.10
+	Hs
		436497 RHOC_HUMAN (13-190): 2.73e-89: 261: 48.13		RGAP1_HUMAN (943-1119): 3.69e-16: 86.3: 35.00
+	Hs
		892584 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RGAP1_HUMAN (943-1119): 3.69e-16: 86.3: 35.00
+	Hs
		892420 RAC3_HUMAN (10-176): 1.96e-89: 261: 53.98		RHG21_HUMAN (195-928): 3.23e-10: 67.6: 11.32