Interactor 1: RBF (Q24472)
Retinoblastoma family protein
Gene: RBF

Interactor 2: E2F1 (Q27368)
Transcription factor E2f1 (dE2F)
Gene: E2F1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 18665226, 8675008, 25242320, 17185321, 17517653, 20861300, 24027329, 29420631, 15456884, 15479636, 15545624, unassigned4
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007307 - eggshell chorion gene amplification
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 845
Dm

1 805
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Ce
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024