Interactor 1: CAF1 (Q24572)
Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55)
Gene: Caf1-55

Interactor 2: SUZ12 (Q9NJG9)
Polycomb protein Su(z)12 (Suppressor 12 of zeste protein)
Gene: Su(z)12

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 21550984, 21549310, 15776017
Identification Methods pull down, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1C_H4-bd~VEFS-Box, VEFS-Box~WD40
Common GO terms GO:0005634 - nucleus
GO:0035097 - histone methyltransferase complex
GO:0035098 - ESC/E(Z) complex
GO:0045892 - negative regulation of DNA-templated transcription
GO:0140718 - facultative heterochromatin formation
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 430
Dm

1 900
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ At
+ At

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Last updated: 15 Jul 2024