Protein: RM50
Large ribosomal subunit protein mL50 (39S ribosomal protein L50, mitochondrial) (L50mt) (MRP-L50)

Gene: RM50, MRPL50
Organism: Homo sapiens
Interactions: 228
UniProt ID: Q8N5N7

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005762 - mitochondrial large ribosomal subunit
GO:0005829 - cytosol
GO:0032543 - mitochondrial translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1328279

RM04
Large ribosomal subunit protein uL4m

5

2

High-throughput

0.922

High

1328236

RM43
Large ribosomal subunit protein mL43

3

2

High-throughput

0.871

High

1123349

ICT1
Large ribosomal subunit protein mL62

5

1

High-throughput

0.718

High

1328320

RM27
Large ribosomal subunit protein bL27m

5

1

High-throughput

0.712

High

1328303

RM17
Large ribosomal subunit protein bL17m

4

1

High-throughput

0.699

High

914667

RM12
Large ribosomal subunit protein bL12m

4

1

High-throughput

0.697

High

1287511

RM52
Large ribosomal subunit protein mL52

4

1

High-throughput

0.697

High

1328287

RM18
Large ribosomal subunit protein uL18m

4

1

High-throughput

0.697

High

1328333

RM42
Large ribosomal subunit protein mL42

4

2

High-throughput

0.691

High

1328315

RM39
Large ribosomal subunit protein mL39

5

0

High-throughput

0.688

High

1328300

RT30
Large ribosomal subunit protein mL65

5

0

High-throughput

0.686

High

350924

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

4

0

High-throughput

0.670

High

882340

RM19
Large ribosomal subunit protein bL19m

4

0

High-throughput

0.670

High

1094057

RM28
Large ribosomal subunit protein bL28m

4

0

High-throughput

0.670

High

1104016

RM49
Large ribosomal subunit protein mL49

4

0

High-throughput

0.670

High

1275798

RM21
Large ribosomal subunit protein bL21m

4

0

High-throughput

0.670

High

1328241

RM30
Large ribosomal subunit protein uL30m

4

0

High-throughput

0.670

High

1328255

MTEF3
Transcription termination factor 3, mitochondrial

4

0

High-throughput

0.670

High

1328295

RM44
Large ribosomal subunit protein mL44

4

0

High-throughput

0.670

High

1328299

RM47
Large ribosomal subunit protein uL29m

4

0

High-throughput

0.670

High

1328307

RT18A
Large ribosomal subunit protein mL66

4

0

High-throughput

0.670

High

1196124

RM51
Large ribosomal subunit protein mL51

4

0

High-throughput

0.667

High

1213286

RM02
Large ribosomal subunit protein uL2m

4

0

High-throughput

0.667

High

1281290

RM10
Large ribosomal subunit protein uL10m

4

0

High-throughput

0.667

High

1312709

RM41
Large ribosomal subunit protein mL41

4

0

High-throughput

0.667

High

1328277

RM13
Large ribosomal subunit protein uL13m

4

0

High-throughput

0.667

High

75996

B4DEF8
Large ribosomal subunit protein mL45

3

1

High-throughput

0.656

High

280044

RM33
Large ribosomal subunit protein bL33m

3

0

High-throughput

0.646

High

477823

RM03
Large ribosomal subunit protein uL3m

3

0

High-throughput

0.646

High

1158238

RM23
Large ribosomal subunit protein uL23m

3

0

High-throughput

0.646

High

1281105

RM55
Large ribosomal subunit protein mL55

3

0

High-throughput

0.646

High

1328240

G45IP
Large ribosomal subunit protein mL64

3

0

High-throughput

0.646

High

1328247

RM24
Large ribosomal subunit protein uL24m

3

0

High-throughput

0.646

High

1328253

RM38
Large ribosomal subunit protein mL38

3

0

High-throughput

0.646

High

1328257

RM53
Large ribosomal subunit protein mL53

3

0

High-throughput

0.646

High

1328260

RM48
Large ribosomal subunit protein mL48

3

0

High-throughput

0.646

High

1328267

RM34
Large ribosomal subunit protein bL34m

3

0

High-throughput

0.646

High

1328275

RM32
Large ribosomal subunit protein bL32m

3

0

High-throughput

0.646

High

1328276

RM20
Large ribosomal subunit protein bL20m

3

0

High-throughput

0.646

High

1328278

RM09
Large ribosomal subunit protein bL9m

3

0

High-throughput

0.646

High

1328280

RM01
Large ribosomal subunit protein uL1m

3

0

High-throughput

0.646

High

1328282

RM37
Large ribosomal subunit protein mL37

3

0

High-throughput

0.646

High

1328289

RM46
Large ribosomal subunit protein mL46

3

0

High-throughput

0.646

High

1328302

RM40
Large ribosomal subunit protein mL40

3

0

High-throughput

0.646

High

1328310

RM22
Large ribosomal subunit protein uL22m

3

0

High-throughput

0.646

High

1328311

RM16
Large ribosomal subunit protein uL16m

3

0

High-throughput

0.646

High

1328318

RM35
Large ribosomal subunit protein bL35m

3

0

High-throughput

0.646

High

1328319

RM15
Large ribosomal subunit protein uL15m

3

0

High-throughput

0.646

High

1328268

RT63
Large ribosomal subunit protein mL63

3

0

High-throughput

0.638

High

1328301

NGRN
Neugrin

3

0

High-throughput

0.638

High

1328328

RM11
Large ribosomal subunit protein uL11m

3

0

High-throughput

0.638

High

61962

GTPBA
GTP-binding protein 10

2

1

High-throughput

0.628

High

271074

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

2

1

High-throughput

0.628

High

1328316

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

2

3

High-throughput

0.611

High

357860

CYB
Cytochrome b

2

0

High-throughput

0.602

High

1027590

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

0

High-throughput

0.602

High

1141511

OXA1L
Mitochondrial inner membrane protein OXA1L

2

0

High-throughput

0.602

High

1240836

RM14
Large ribosomal subunit protein uL14m

2

0

High-throughput

0.602

High

1328256

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

2

0

High-throughput

0.602

High

1328298

MRM3
rRNA methyltransferase 3, mitochondrial

2

0

High-throughput

0.602

High

1328317

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

0

High-throughput

0.602

High

686272

RL13
Large ribosomal subunit protein eL13

2

0

High-throughput

0.585

High

72958

B1AL05
Large ribosomal subunit protein mL43

1

2

High-throughput

0.575

High

1328269

RM45
Large ribosomal subunit protein mL45

2

1

High-throughput

0.552

High

1050814

PTN12
Tyrosine-protein phosphatase non-receptor type 12

2

0

High-throughput

0.547

High

994658

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.536

High

1099158

SRSF5
Serine/arginine-rich splicing factor 5

1

1

High-throughput

0.536

High

1240306

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.536

High

1328296

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.536

High

117328

K7ES61
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.514

High

250706

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

321854

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

0

High-throughput

0.513

High

397746

NU5M
NADH-ubiquinone oxidoreductase chain 5

1

0

High-throughput

0.513

High

485267

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.513

High

615868

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

842439

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

858986

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

906243

SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

945153

CORO7
Coronin-7

1

0

High-throughput

0.513

High

960488

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.513

High

964130

RL37
Large ribosomal subunit protein eL37

1

0

High-throughput

0.513

High

969307

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

995442

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.513

High

1011662

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.513

High

1012725

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.513

High

1016105

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1101466

KCAB2
Voltage-gated potassium channel subunit beta-2

1

0

High-throughput

0.513

High

1113689

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1130104

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

1137642

EXOS7
Exosome complex component RRP42

1

0

High-throughput

0.513

High

1148728

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

0

High-throughput

0.513

High

1162663

THTR
Thiosulfate sulfurtransferase

1

0

High-throughput

0.513

High

1224751

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

1240532

RM54
Large ribosomal subunit protein mL54

1

0

High-throughput

0.513

High

1270581

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

1290075

THOC4
THO complex subunit 4

1

0

High-throughput

0.513

High

1311140

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.513

High

1328242

ZC3HF
Zinc finger CCCH domain-containing protein 15

1

0

High-throughput

0.513

High

1328243

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

0

High-throughput

0.513

High

1328258

MOCOS
Molybdenum cofactor sulfurase

1

0

High-throughput

0.513

High

1328261

RCC1L
RCC1-like G exchanging factor-like protein

1

0

High-throughput

0.513

High

1328327

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1328329

TLN1
Talin-1

1

0

High-throughput

0.513

High

1328330

KLF12
Krueppel-like factor 12

1

1

High-throughput

0.500

High

1016517

SRSF3
Serine/arginine-rich splicing factor 3

1

3

High-throughput

0.489

High

1160001

SRSF7
Serine/arginine-rich splicing factor 7

1

1

High-throughput

0.489

High

1328326

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.489

High

282007

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

284178

SRS10
Serine/arginine-rich splicing factor 10

1

1

High-throughput

0.479

High

287331

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

856312

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

939808

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

1

High-throughput

0.479

High

962269

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

1015597

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

1083670

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1135907

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

1234451

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1272937

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

1328238

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1328245

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.479

High

1328246

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1328250

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1328251

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1328263

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1328290

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1328291

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.479

High

1328308

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1328322

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.479

High

1328323

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1328332

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

61553

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66238

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

134798

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

183683

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

275983

DUS11
RNA/RNP complex-1-interacting phosphatase

1

0

High-throughput

0.458

High

279831

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

317890

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

447219

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

519164

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532771

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

786170

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

828852

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841829

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851952

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882779

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

960171

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

970779

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1024102

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048595

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1051267

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.458

High

1058139

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1087457

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1106611

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1117780

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1140558

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1142600

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1145274

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.458

High

1149594

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1207073

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1229564

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1241314

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.458

High

1271454

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1275560

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.458

High

1310227

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1328239

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1328248

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1328249

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1328252

FMT
Methionyl-tRNA formyltransferase, mitochondrial

1

0

High-throughput

0.458

High

1328254

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1328259

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

1328262

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1328264

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1328270

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1328271

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1328272

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1328273

TR61B
tRNA

1

0

High-throughput

0.458

High

1328274

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1328281

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1328283

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1328284

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1328285

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1328288

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1328293

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1328294

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1328304

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

1328305

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1328309

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1328321

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1328324

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

76296

B4DLN1
Mitochondrial dicarboxylate carrier

1

2

High-throughput

0.445

High

116981

J3KPP0
Large ribosomal subunit protein mL42

1

2

High-throughput

0.445

High

331143

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

372577

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406390

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

988156

TRA2B
Transformer-2 protein homolog beta

1

1

High-throughput

0.437

High

1111810

TRA2A
Transformer-2 protein homolog alpha

1

1

High-throughput

0.437

High

1215711

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1328297

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

135277

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.426

High

1328306

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.426

High

1328325

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.426

High

94388

D6RAN8
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.407

High

108061

G3V325
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

2

High-throughput

0.407

High

117042

J3KS15
Large ribosomal subunit protein mL62

1

1

High-throughput

0.407

High

1260373

H1FNT
Testis-specific H1 histone

2

0

High-throughput

0.313

High

703961

DUS1
Dual specificity protein phosphatase 1

2

0

High-throughput

0.298

High

220062

XRCC2
DNA repair protein XRCC2

1

0

High-throughput

0.279

Low

344418

TBCD8
TBC1 domain family member 8

1

0

High-throughput

0.279

Low

376404

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

517785

GLI4
Zinc finger protein GLI4

1

0

High-throughput

0.279

Low

1009251

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1162833

H2A2C
Histone H2A type 2-C

1

0

High-throughput

0.279

Low

1238310

REEP3
Receptor expression-enhancing protein 3

1

0

High-throughput

0.279

Low

1325126

MILK1
MICAL-like protein 1

1

0

High-throughput

0.279

Low

1328237

TEX19
Testis-expressed protein 19

1

0

High-throughput

0.279

Low

1328265

FOXB1
Forkhead box protein B1

1

0

High-throughput

0.279

Low

1328266

GDF15
Growth/differentiation factor 15

1

0

High-throughput

0.279

Low

1328292

THAP9
DNA transposase THAP9

1

0

High-throughput

0.279

Low

1328314

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.279

Low

1328331

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.279

Low

1042891

ERCC6
DNA excision repair protein ERCC-6

1

0

High-throughput

0.261

Low

472889

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low

1156773

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1328244

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.249

Low

1328286

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.249

Low

1328312

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

0

High-throughput

0.249

Low

1328313

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low

1034498

TAGL
Transgelin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025