HitPredict

Interactor 1: Q29QQ9 (Q29QQ9)
Ribosomal RNA-processing protein 42
Gene: Rrp42

Interactor 2: Q9VW53 (Q9VW53)
FI01414p (Mtr3)
Gene: Mtr3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.775

Property	Details
Experiments	14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RNase_PH~RNase_PH, RNase_PH~RNase_PH_C
Common GO terms	GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0005737 - cytoplasm GO:0034475 - U4 snRNA 3'-end processing and 1 others more... GO:0071028 - nuclear mRNA surveillance
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 296 Dm			1 326
+	Hs
		1284978 EXOS8_HUMAN (1-283): 8.6e-87: 262: 25.35		EXOS4_HUMAN (32-280): 1.32e-66: 211: 23.32
+	Hs
		1063768 EXOS7_HUMAN (1-295): 1.18e-85: 260: 48.14		EXOS4_HUMAN (32-280): 1.32e-66: 211: 23.32
+	Dm
		1100455 Q29QQ9_DROME (1-296): 1.88e-89: 270: 100.00		Q9VK19_DROME (33-278): 1.24e-61: 198: 24.50
+	Dm
		1100452 Q29QQ9_DROME (1-296): 1.88e-89: 270: 100.00		Q8SYC8_DROME (33-278): 2.73e-61: 197: 24.50
+	At
		1337646 CER7L_ARATH (6-291): 1.75e-81: 250: 23.61		RRP41_ARATH (33-280): 1.97e-68: 215: 23.11
+	At
		1340946 CER7_ARATH (6-291): 1.26e-77: 244: 24.31		RRP41_ARATH (33-280): 1.97e-68: 215: 23.11
+	At
		1324946 Q9FPI0_ARATH (4-286): 1.98e-75: 233: 33.68		RRP41_ARATH (33-280): 1.97e-68: 215: 23.11
+	Hs
		986725 EXOS9_HUMAN (1-286): 6.52e-71: 227: 25.35		EXOS4_HUMAN (32-280): 1.32e-66: 211: 23.32
+	Sp
		194779 RRP45_SCHPO (2-287): 3.84e-75: 233: 21.88		RRP41_SCHPO (32-278): 6.61e-63: 201: 22.00
+	Hs
		1284945 EXOS8_HUMAN (1-283): 8.6e-87: 262: 25.35		EXOS8_HUMAN (12-263): 1.08e-46: 160: 15.79
+	Hs
		1063750 EXOS8_HUMAN (1-283): 8.6e-87: 262: 25.35		EXOS7_HUMAN (17-287): 2.66e-43: 152: 15.17
+	Hs
		1284980 EXOS8_HUMAN (1-283): 8.6e-87: 262: 25.35		EXOS5_HUMAN (16-222): 3.05e-43: 150: 21.15
+	Hs
		1063771 EXOS7_HUMAN (1-295): 1.18e-85: 260: 48.14		EXOS5_HUMAN (16-222): 3.05e-43: 150: 21.15
+	Hs
		1130042 EXOS8_HUMAN (1-283): 8.6e-87: 262: 25.35		EXOS6_HUMAN (12-272): 5.32e-35: 129: 23.11
+	Hs
		1063723 EXOS7_HUMAN (1-295): 1.18e-85: 260: 48.14		EXOS6_HUMAN (12-272): 5.32e-35: 129: 23.11
+	Hs
		986709 EXOS9_HUMAN (1-286): 6.52e-71: 227: 25.35		EXOS8_HUMAN (12-263): 1.08e-46: 160: 15.79
+	Hs
		986677 EXOS9_HUMAN (1-286): 6.52e-71: 227: 25.35		EXOS7_HUMAN (17-287): 2.66e-43: 152: 15.17
+	Hs
		986727 EXOS9_HUMAN (1-286): 6.52e-71: 227: 25.35		EXOS5_HUMAN (16-222): 3.05e-43: 150: 21.15
+	Hs
		986681 EXOS9_HUMAN (1-286): 6.52e-71: 227: 25.35		EXOS6_HUMAN (12-272): 5.32e-35: 129: 23.11