HitPredict

Interactor 1: UBXN3 (H2L056)
UBX domain-containing protein 3
Gene: ubxn-3

Interactor 2: TERA2 (P54812)
Transitional endoplasmic reticulum ATPase homolog 2 (EC 3.6.4.6) (Cell division cycle-related protein 48.2) (p97/CDC48 homolog 2)
Gene: cdc-48.2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	20977550
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	CDC48_2~UBX, CDC48_N~UBX
Common GO terms	GO:0005634 - nucleus GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Ce			1 810
+	Ce
		110126 UBXN3_CAEEL (1-613): 0: 654: 100.00		TERA1_CAEEL (1-810): 0: 732: 87.69
+	Hs
		875432 FAF1_HUMAN (154-611): 3.87e-136: 413: 26.96		TERA_HUMAN (12-788): 0: 727: 78.79
+	Mm
		872336 FAF1_MOUSE (154-611): 1.64e-133: 406: 26.96		TERA_MOUSE (12-788): 0: 727: 78.79
+	Hs
		299344 UBXN7_HUMAN (236-612): 1.45e-71: 240: 12.45		TERA_HUMAN (12-788): 0: 727: 78.79
+	At
		67566 A8MRM0_ARATH (275-605): 6.08e-67: 227: 15.27		CD48A_ARATH (1-791): 0: 731: 71.88
+	At
		870959 PUX7_ARATH (275-605): 1.38e-66: 226: 15.27		CD48A_ARATH (1-791): 0: 731: 71.88
+	Hs
		875209 FAF2_HUMAN (275-613): 2.46e-68: 230: 21.63		TERA_HUMAN (12-788): 0: 727: 78.79
+	Sc
		636736 UBX2_YEAST (201-613): 9.9e-66: 227: 12.33		CDC48_YEAST (6-810): 0: 715: 64.89
+	Sp
		144230 UBX2_SCHPO (209-609): 2.93e-72: 240: 13.90		CDC48_SCHPO (1-810): 0: 700: 64.37
+	Dm
		1180101 Q7K4I5_DROME (215-610): 1.25e-57: 203: 10.71		TERA_DROME (12-810): 0: 734: 78.30
+	Sc
		636779 UBX3_YEAST (276-613): 7.58e-54: 192: 17.83		CDC48_YEAST (6-810): 0: 715: 64.89
+	Ce
		712422 UBXN4_CAEEL (374-610): 7.66e-38: 148: 11.97		TERA2_CAEEL (1-791): 0: 746: 100.00
+	Sc
		636759 UBX5_YEAST (301-613): 8.05e-47: 173: 12.15		CDC48_YEAST (6-810): 0: 715: 64.89
+	Sp
		251597 UCP10_SCHPO (282-597): 3.33e-50: 181: 17.45		CDC48_SCHPO (1-810): 0: 700: 64.37
+	Ce
		712421 UBXN4_CAEEL (374-610): 7.66e-38: 148: 11.97		TERA1_CAEEL (1-810): 0: 732: 87.69
+	Sc
		636664 UBX6_YEAST (375-613): 1.23e-38: 148: 11.84		CDC48_YEAST (6-810): 0: 715: 64.89
+	Hs
		116676 UBXN8_HUMAN (401-612): 5.92e-35: 135: 17.12		TERA_HUMAN (12-788): 0: 727: 78.79
+	Sc
		636608 UBX7_YEAST (370-613): 4.5e-36: 142: 11.63		CDC48_YEAST (6-810): 0: 715: 64.89
+	Ce
		873000 UBXN5_CAEEL (458-601): 4.08e-24: 101: 19.44		TERA1_CAEEL (1-810): 0: 732: 87.69
+	Hs
		875167 UBXN4_HUMAN (456-610): 3.77e-23: 105: 12.79		TERA_HUMAN (12-788): 0: 727: 78.79