Interactor 1: ACHA5 (Q2MKA5)
Neuronal acetylcholine receptor subunit alpha-5
Gene: Chrna5

Interactor 2: ACHA3 (Q8R4G9)
Neuronal acetylcholine receptor subunit alpha-3
Gene: Chrna3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17434683
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0007271 - synaptic transmission, cholinergic
GO:0015464 - acetylcholine receptor activity
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
and 14 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 467
Mm

1 499
+ Hs
+ Gg
+ Hs
+ Gg
+ Rn
+ Rn
+ Hs
+ Hs
+ Gg
+ Gg
+ Rn
+ Gg
+ Hs
+ Rn
+ Rn
+ Mm
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024