Protein: DNJB5
DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)

Gene: DNJB5, DNAJB5
Organism: Homo sapiens
Interactions: 121
UniProt ID: O75953

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006986 - response to unfolded protein
GO:0051082 - unfolded protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

298969

DNJB4
DnaJ homolog subfamily B member 4

6

12

High-throughput

0.945

High

298887

DNJB1
DnaJ homolog subfamily B member 1

5

12

High-throughput

0.927

High

298943

HS105
Heat shock protein 105 kDa

2

20

High-throughput

0.802

High

298877

HERC2
E3 ubiquitin-protein ligase HERC2

2

10

High-throughput

0.789

High

298882

HSP7C
Heat shock cognate 71 kDa protein

2

20

High-throughput

0.737

High

298925

OBSCN
Obscurin

1

7

High-throughput

0.698

High

298942

TITIN
Titin

1

7

High-throughput

0.698

High

298982

ASB4
Ankyrin repeat and SOCS box protein 4

4

16

High-throughput

0.694

High

298891

HSP74
Heat shock 70 kDa protein 4

1

20

High-throughput

0.691

High

298922

TFDP3
Transcription factor Dp family member 3

3

3

High-throughput

0.667

High

298951

DNJC7
DnaJ homolog subfamily C member 7

1

19

High-throughput

0.665

High

174205

ARHGA
Rho guanine nucleotide exchange factor 10

3

8

High-throughput

0.656

High

298893

TKTL1
Transketolase-like protein 1

2

4

High-throughput

0.628

High

298930

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

8

High-throughput

0.628

High

298953

NPAS1
Neuronal PAS domain-containing protein 1

2

9

High-throughput

0.628

High

298974

FBW1B
F-box/WD repeat-containing protein 11

2

12

High-throughput

0.628

High

298884

HSP76
Heat shock 70 kDa protein 6

1

20

Small-scale

0.618

High

298890

HS71L
Heat shock 70 kDa protein 1-like

1

20

High-throughput

0.618

High

298894

HSP72
Heat shock-related 70 kDa protein 2

1

20

High-throughput

0.618

High

298903

DNJC3
DnaJ homolog subfamily C member 3

1

20

High-throughput

0.618

High

298964

DJB12
DnaJ homolog subfamily B member 12

1

17

High-throughput

0.618

High

194428

P2RX6
P2X purinoceptor 6

3

1

High-throughput

0.609

High

298941

TB22A
TBC1 domain family member 22A

3

4

High-throughput

0.609

High

298889

STIP1
Stress-induced-phosphoprotein 1

2

20

High-throughput

0.584

High

231543

PRKY
Putative serine/threonine-protein kinase PRKY

1

11

High-throughput

0.575

High

298902

KCNC4
Voltage-gated potassium channel KCNC4

2

4

High-throughput

0.574

High

298917

TR16L
Tripartite motif-containing protein 16-like protein

2

6

High-throughput

0.574

High

298928

KLH10
Kelch-like protein 10

2

5

High-throughput

0.574

High

298958

MANS1
MANSC domain-containing protein 1

2

1

High-throughput

0.574

High

298929

TBPL2
TATA box-binding protein-like 2

1

1

Small-scale

0.561

High

298984

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

1

High-throughput

0.549

High

298885

TAF1
Transcription initiation factor TFIID subunit 1

1

7

High-throughput

0.541

High

298899

SMAD3
Mothers against decapentaplegic homolog 3

1

4

High-throughput

0.541

High

298900

MYPC1
Myosin-binding protein C, slow-type

1

6

High-throughput

0.541

High

298901

ANK2
Ankyrin-2

1

3

High-throughput

0.541

High

298913

SMAD2
Mothers against decapentaplegic homolog 2

1

4

High-throughput

0.541

High

298972

NOCT
Nocturnin

1

3

High-throughput

0.541

High

191271

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

2

High-throughput

0.536

High

298876

BAG4
BAG family molecular chaperone regulator 4

1

10

High-throughput

0.536

High

298923

CC038
Uncharacterized protein C3orf38

1

1

High-throughput

0.536

High

298924

ZN658
Zinc finger protein 658

1

2

High-throughput

0.536

High

298955

DUS16
Dual specificity protein phosphatase 16

1

2

High-throughput

0.536

High

298963

ING3
Inhibitor of growth protein 3

1

1

High-throughput

0.536

High

298927

Q6ICH2
single-stranded DNA cytosine deaminase

2

9

High-throughput

0.533

High

139670

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.529

High

156226

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

4

High-throughput

0.515

High

298976

CHIP
E3 ubiquitin-protein ligase CHIP

1

11

High-throughput

0.515

High

298967

RBPJL
Recombining binding protein suppressor of hairless-like protein

1

0

High-throughput

0.513

High

298973

FBX10
F-box only protein 10

1

0

High-throughput

0.513

High

168791

PLD2
Phospholipase D2

1

6

High-throughput

0.489

High

175515

TCPR2
Tectonin beta-propeller repeat-containing protein 2

1

1

High-throughput

0.489

High

298905

PLD1
Phospholipase D1

1

6

High-throughput

0.489

High

298919

WDR72
WD repeat-containing protein 72

1

10

High-throughput

0.489

High

298920

KHDC1
KH homology domain-containing protein 1

1

1

High-throughput

0.489

High

298932

NALP8
NACHT, LRR and PYD domains-containing protein 8

1

6

High-throughput

0.489

High

298952

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

3

High-throughput

0.489

High

298965

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

4

High-throughput

0.489

High

124698

AIP
AH receptor-interacting protein

1

11

High-throughput

0.479

High

165218

PSA7
Proteasome subunit alpha type-7

1

3

High-throughput

0.479

High

298878

BAG2
BAG family molecular chaperone regulator 2

1

8

High-throughput

0.479

High

298879

ISG15
Ubiquitin-like protein ISG15

1

13

Small-scale

0.479

High

298881

CLCA
Clathrin light chain A

1

2

High-throughput

0.479

High

298888

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

High-throughput

0.479

High

298892

EMD
Emerin

1

1

High-throughput

0.479

High

298895

HDAC4
Histone deacetylase 4

1

9

Small-scale

0.479

High

298897

MTPN
Myotrophin

1

6

High-throughput

0.479

High

298898

RS25
Small ribosomal subunit protein eS25

1

2

High-throughput

0.479

High

298904

SKP2
S-phase kinase-associated protein 2

1

4

Small-scale

0.479

High

298906

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

15

High-throughput

0.479

High

298909

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

14

High-throughput

0.479

High

298912

MLF2
Myeloid leukemia factor 2

1

7

High-throughput

0.479

High

298914

CDC37
Hsp90 co-chaperone Cdc37

1

3

High-throughput

0.479

High

298918

EDRF1
Erythroid differentiation-related factor 1

1

2

High-throughput

0.479

High

298935

ASPM
Abnormal spindle-like microcephaly-associated protein

1

2

High-throughput

0.479

High

298944

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

High-throughput

0.479

High

298947

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

High-throughput

0.479

High

298950

CK5P2
CDK5 regulatory subunit-associated protein 2

1

8

High-throughput

0.479

High

298956

ZN644
Zinc finger protein 644

1

5

High-throughput

0.479

High

298959

GRPE1
GrpE protein homolog 1, mitochondrial

1

2

High-throughput

0.479

High

298961

WDR6
tRNA

1

18

High-throughput

0.479

High

298962

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.479

High

298975

BAG5
BAG family molecular chaperone regulator 5

1

10

High-throughput

0.479

High

298978

CP131
Centrosomal protein of 131 kDa

1

4

High-throughput

0.479

High

298979

CBPC1
Cytosolic carboxypeptidase 1

1

1

High-throughput

0.479

High

298981

SGT1
Protein SGT1 homolog

1

11

High-throughput

0.479

High

298911

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.458

High

298915

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

298954

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.458

High

298960

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

298966

NCDN
Neurochondrin

1

0

High-throughput

0.458

High

298883

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.445

High

298896

MLF1
Myeloid leukemia factor 1

1

7

High-throughput

0.445

High

298907

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

8

High-throughput

0.445

High

298926

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.445

High

298945

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

9

High-throughput

0.445

High

298949

KLH15
Kelch-like protein 15

1

11

High-throughput

0.445

High

298886

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

4

High-throughput

0.437

High

298908

RCN2
Reticulocalbin-2

1

7

High-throughput

0.437

High

298933

PLD3
5'-3' exonuclease PLD3

1

2

High-throughput

0.437

High

298936

NIN
Ninein

1

6

High-throughput

0.437

High

298946

ENTR1
Endosome-associated-trafficking regulator 1

1

2

High-throughput

0.437

High

298970

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

5

High-throughput

0.437

High

298971

S12A6
Solute carrier family 12 member 6

1

6

Small-scale

0.437

High

73364

B2CML4
single-stranded DNA cytosine deaminase

1

9

High-throughput

0.407

High

96805

E9PB39
Rho guanine nucleotide exchange factor 10

1

8

High-throughput

0.407

High

298937

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

298968

SL9A2
Sodium/hydrogen exchanger 2

1

6

High-throughput

0.407

High

298977

S12A4
Solute carrier family 12 member 4

1

6

High-throughput

0.407

High

298980

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.407

High

298983

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.282

High

298880

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

298916

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

298921

UROL1
Uromodulin-like 1

1

0

High-throughput

0.279

Low

298931

TLCD5
TLC domain-containing protein 5

1

0

High-throughput

0.279

Low

298934

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

298938

ACV1C
Activin receptor type-1C

1

0

High-throughput

0.279

Low

298948

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

298939

KC5S1
Uncharacterized protein KCNJ5-AS1

1

0

High-throughput

0.269

Low

298910

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.249

Low

298940

DLG5
Disks large homolog 5

1

0

High-throughput

0.249

Low

298957

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025