HitPredict

Interactor 1: CKB12 (Q2V419)
Cyclin-dependent kinase B1-2 (CDKB1;2) (EC 2.7.11.22) (EC 2.7.11.23)
Gene: CDKB1-2

Interactor 2: CCD61 (Q9ZR04)
Putative cyclin-D6-1 (G1/S-specific cyclin-D6-1) (CycD6;1)
Gene: CYCD6-1

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20407024
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 311 At			1 302
+	Hs
		538471 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNB1_HUMAN (3-294): 7.9e-84: 260: 16.27
+	Hs
		625350 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNA1_HUMAN (3-292): 5.63e-83: 259: 16.04
+	At
		1103349 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA23_ARATH (8-293): 1.73e-82: 257: 16.26
+	Hs
		303829 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNB2_HUMAN (7-294): 1.71e-80: 250: 16.50
+	At
		1059417 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA22_ARATH (1-301): 2.84e-82: 256: 19.74
+	At
		1103352 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA21_ARATH (12-301): 5.84e-80: 250: 20.14
+	Hs
		590125 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNA2_HUMAN (6-292): 5.36e-77: 243: 17.93
+	At
		1103350 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB12_ARATH (8-276): 2.02e-79: 249: 20.22
+	At
		1103360 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCD41_ARATH (6-289): 1.4e-80: 248: 29.76
+	At
		672516 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB11_ARATH (8-279): 8.26e-79: 247: 22.91
+	At
		1103353 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCA34_ARATH (11-289): 2.69e-79: 246: 19.65
+	Rn
		70081 Q6P751_RAT (1-309): 6.79e-149: 421: 56.77		B1WC54_RAT (8-294): 4.25e-71: 227: 16.61
+	At
		1013000 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCD42_ARATH (10-280): 1.33e-74: 232: 26.18
+	Hs
		624539 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCNE1_HUMAN (8-296): 5.94e-68: 219: 17.85
+	At
		1103351 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCB22_ARATH (8-282): 4.41e-65: 212: 16.55
+	Rn
		981205 Q6P751_RAT (1-309): 6.79e-149: 421: 56.77		CCND2_RAT (24-265): 1.48e-62: 201: 20.70
+	Hs
		625155 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCND2_HUMAN (29-287): 1.29e-59: 193: 22.85
+	At
		1103315 CKB12_ARATH (1-311): 1.9e-146: 415: 100.00		CCD51_ARATH (45-297): 1.34e-50: 171: 24.25
+	Hs
		625156 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCND3_HUMAN (29-286): 2.27e-46: 159: 20.90
+	Hs
		622358 CDK2_HUMAN (1-309): 2.25e-149: 422: 56.77		CCND1_HUMAN (29-296): 2.04e-41: 146: 21.25