HitPredict

Interactor 1: SETB1 (Q32KD2)
Histone-lysine N-methyltransferase eggless (EC 2.1.1.355) (SETDB1 homolog)
Gene: egg

Interactor 2: Q9VCU6 (Q9VCU6)
Heterochromatin protein 1c (LD23881p)
Gene: HP1c

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30659116
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1262 Dm			1 237
+	Dm
		1103808 SETB1_DROME (1-1262): 0: 1747: 100.00		Q9W396_DROME (7-135): 2.08e-37: 132: 40.54
+	Dm
		399003 SETB1_DROME (1-1262): 0: 1747: 100.00		HP1_DROME (8-135): 8.08e-29: 109: 29.71
+	Mm
		1376692 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		CDYL_MOUSE (4-197): 1.07e-51: 178: 22.84
+	Hs
		1334148 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		CDY2_HUMAN (5-203): 1.72e-47: 166: 15.84
+	Mm
		1322051 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		CDYL2_MOUSE (1-196): 3.97e-45: 159: 20.67
+	Hs
		1027268 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Mm
		1322180 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		Q9DCC5_MOUSE (4-135): 9.89e-43: 144: 39.46
+	Hs
		1027194 EHMT2_HUMAN (1100-1258): 1.38e-44: 178: 21.95		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		800530 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Mm
		1143050 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		CBX5_MOUSE (8-155): 9.64e-38: 132: 31.79
+	Hs
		949889 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		CBX1_HUMAN (14-144): 1.27e-37: 131: 35.10
+	Hs
		800497 EHMT2_HUMAN (1100-1258): 1.38e-44: 178: 21.95		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Mm
		949963 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		CBX1_MOUSE (14-144): 1.27e-37: 131: 35.10
+	Hs
		949863 EHMT2_HUMAN (1100-1258): 1.38e-44: 178: 21.95		CBX1_HUMAN (14-144): 1.27e-37: 131: 35.10
+	Hs
		1331975 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		SUV92_HUMAN (3-125): 5.06e-31: 119: 22.76
+	Hs
		203794 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		SUV91_HUMAN (3-124): 2.33e-30: 118: 22.13
+	Hs
		1296419 EHMT2_HUMAN (1100-1258): 1.38e-44: 178: 21.95		SUV92_HUMAN (3-125): 5.06e-31: 119: 22.76
+	Mm
		1112138 EHMT2_MOUSE (1100-1258): 9.88e-45: 179: 21.95		MPP8_MOUSE (3-161): 2.47e-29: 117: 22.89
+	Hs
		203766 EHMT2_HUMAN (1100-1258): 1.38e-44: 178: 21.95		SUV91_HUMAN (3-124): 2.33e-30: 118: 22.13
+	Hs
		1304468 EHMT1_HUMAN (1085-1258): 6.22e-45: 180: 22.91		MPP8_HUMAN (5-82): 2.86e-12: 67.7: 36.71