HitPredict

Interactor 1: EMAL3 (Q32P44)
Echinoderm microtubule-associated protein-like 3 (EMAP-3)
Gene: EML3

Interactor 2: NEK1 (Q96PY6)
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)
Gene: NEK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 1258
+	Hs
		1104134 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK9_HUMAN (4-261): 3.69e-61: 229: 42.31
+	Hs
		1104135 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK7_HUMAN (8-262): 1.88e-52: 188: 38.31
+	Hs
		1104147 EMAL3_HUMAN (1-896): 0: 558: 100.00		NEK6_HUMAN (8-267): 7.24e-52: 187: 36.84
+	Hs
		148197 WDR1_HUMAN (262-624): 1.44e-44: 172: 10.49		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		148610 WDR5_HUMAN (60-390): 5.42e-34: 135: 11.34		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		149156 SNR40_HUMAN (765-888): 8.65e-20: 93.9: 11.29		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		148858 TAF5_HUMAN (339-690): 8.75e-16: 84.2: 16.44		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		148734 TBL3_HUMAN (92-298): 1.15e-15: 83.9: 8.33		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		254137 WDR1_HUMAN (262-624): 1.44e-44: 172: 10.49		AKT3_HUMAN (1-316): 3.67e-120: 383: 27.03
+	Hs
		149418 PRP19_HUMAN (361-664): 3.33e-12: 71.8: 15.71		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Hs
		149427 WDR3_HUMAN (163-287): 7.78e-11: 68.1: 12.88		CTRO_HUMAN (2-1006): 2.42e-143: 481: 16.04
+	Dm
		1213409 NLE_DROME (151-252): 4.56e-11: 68.1: 13.46		AKT1_DROME (1-321): 7.3e-122: 392: 25.30
+	Hs
		851739 PRP19_HUMAN (361-664): 3.33e-12: 71.8: 15.71		NEK4_HUMAN (1-266): 1.31e-78: 279: 50.56
+	Hs
		1254380 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK9_HUMAN (4-261): 3.69e-61: 229: 42.31
+	Hs
		325574 EMAL2_HUMAN (587-896): 6.05e-26: 116: 13.62		NEK6_HUMAN (8-267): 7.24e-52: 187: 36.84
+	Hs
		127925 EMAL1_HUMAN (760-894): 5.57e-09: 61.9: 8.11		NEK9_HUMAN (4-261): 3.69e-61: 229: 42.31
+	Hs
		1255597 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK7_HUMAN (8-262): 1.88e-52: 188: 38.31
+	Hs
		1335710 EMAL4_HUMAN (180-462): 2.49e-20: 98.9: 9.51		NEK6_HUMAN (8-267): 7.24e-52: 187: 36.84
+	Sc
		561843 TUP1_YEAST (461-707): 3.26e-23: 107: 19.27		KIN3_YEAST (3-254): 1.18e-34: 140: 31.65