HitPredict

Interactor 1: AKT2 (Q38898)
Potassium channel AKT2/3
Gene: AKT2

Interactor 2: KAT1 (Q39128)
Potassium channel KAT1
Gene: KAT1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.850

Property	Details
Experiments	17085433, 15299147, 12034902
Identification Methods	two hybrid, protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	cNMP_binding~cNMP_binding, Ion_trans~cNMP_binding, Ion_trans~Ion_trans
Common GO terms	GO:0034702 - monoatomic ion channel complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 802 At			1 677
+	At
		1104868 AKT2_ARATH (1-802): 0: 584: 100.00		KAT2_ARATH (1-677): 0: 540: 74.25
+	At
		1105084 AKT2_ARATH (1-802): 0: 584: 100.00		AKT1_ARATH (11-669): 4.18e-177: 528: 44.36
+	At
		1105083 AKT2_ARATH (1-802): 0: 584: 100.00		AKT2_ARATH (1-666): 6.87e-170: 507: 39.91
+	At
		955267 AKT2_ARATH (1-802): 0: 584: 100.00		KAT3_ARATH (2-674): 4.8e-141: 428: 39.44
+	At
		1277236 GORK_ARATH (17-800): 1.97e-156: 478: 29.33		GORK_ARATH (3-669): 9.61e-150: 456: 26.59
+	At
		1277237 GORK_ARATH (17-800): 1.97e-156: 478: 29.33		SKOR_ARATH (43-668): 8.58e-146: 446: 26.94
+	At
		1341276 SKOR_ARATH (41-800): 2.01e-153: 470: 29.31		SKOR_ARATH (43-668): 8.58e-146: 446: 26.94
+	Hs
		1377721 HCN4_HUMAN (1-596): 5.34e-123: 400: 17.44		HCN4_HUMAN (39-645): 2.8e-156: 484: 17.70
+	Hs
		1356781 HCN4_HUMAN (1-596): 5.34e-123: 400: 17.44		HCN2_HUMAN (39-568): 9.39e-143: 440: 19.71
+	Mm
		71335 B2RY58_MOUSE (2-596): 2.01e-122: 398: 17.47		HCN2_MOUSE (39-568): 7.11e-142: 437: 19.71
+	Hs
		240287 HCN4_HUMAN (1-596): 5.34e-123: 400: 17.44		HCN1_HUMAN (39-562): 5.24e-140: 433: 18.64
+	Mm
		71336 B2RY58_MOUSE (2-596): 2.01e-122: 398: 17.47		HCN1_MOUSE (39-564): 1.56e-140: 435: 18.38
+	Mm
		251014 HCN4_MOUSE (2-547): 1.06e-119: 391: 16.81		HCN1_MOUSE (39-564): 1.56e-140: 435: 18.38
+	Hs
		1349966 HCN4_HUMAN (1-596): 5.34e-123: 400: 17.44		HCN3_HUMAN (39-618): 3.66e-135: 417: 16.17
+	Mm
		292103 HCN1_MOUSE (4-560): 3.66e-117: 377: 16.87		HCN2_MOUSE (39-568): 7.11e-142: 437: 19.71
+	Mm
		292110 HCN1_MOUSE (4-560): 3.66e-117: 377: 16.87		HCN1_MOUSE (39-564): 1.56e-140: 435: 18.38
+	Hs
		240252 HCN2_HUMAN (11-561): 1.87e-116: 375: 17.72		HCN1_HUMAN (39-562): 5.24e-140: 433: 18.64