HitPredict

Interactor 1: H2L2C8 (H2L2C8)
Alpha-actinin, sarcomeric
Gene: atn-1

Interactor 2: LIN2 (P54936)
Protein lin-2 (Abnormal cell lineage protein 2)
Gene: lin-2

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	26780296
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030054 - cell junction
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 823 Ce			1 961
+	Ce
		873641 Q9XVU8_CAEEL (1-823): 0: 573: 100.00		LIN2_CAEEL (1-961): 0: 949: 100.00
+	Ce
		873627 Q23158_CAEEL (1-823): 0: 553: 95.41		LIN2_CAEEL (1-961): 0: 949: 100.00
+	Ce
		1089009 Q9XVU8_CAEEL (1-823): 0: 573: 100.00		Q17549_CAEEL (432-959): 1.25e-149: 460: 25.58
+	Ce
		110538 H2L2C8_CAEEL (1-823): 0: 571: 100.00		Q17549_CAEEL (432-959): 1.25e-149: 460: 25.58
+	Ce
		1088998 Q23158_CAEEL (1-823): 0: 553: 95.41		Q17549_CAEEL (432-959): 1.25e-149: 460: 25.58
+	Hs
		211576 ACTN4_HUMAN (82-802): 5.6e-13: 75: 13.23		KCC2B_HUMAN (13-512): 4.47e-161: 489: 25.79
+	Hs
		725649 ACTN2_HUMAN (82-823): 2.15e-16: 85.8: 12.45		DLG1_HUMAN (496-958): 1.14e-151: 473: 23.72
+	Hs
		725643 ACTN2_HUMAN (82-823): 2.15e-16: 85.8: 12.45		DLG4_HUMAN (456-957): 5.65e-144: 447: 22.69
+	Mm
		515254 ACTN2_MOUSE (82-823): 1.88e-16: 86.2: 12.45		KCC2A_MOUSE (15-321): 1.8e-46: 176: 32.48
+	Rn
		88556 D3ZCV0_RAT (82-823): 8.52e-16: 83.9: 12.31		KCC2A_RAT (15-321): 1.8e-46: 176: 32.48
+	Rn
		506781 ACTN1_RAT (82-823): 2.05e-13: 76.2: 12.45		KCC2A_RAT (15-321): 1.8e-46: 176: 32.48
+	Hs
		211695 ACTN4_HUMAN (82-802): 5.6e-13: 75: 13.23		KCC2A_HUMAN (15-321): 1.8e-46: 176: 32.48
+	Hs
		521641 ACTN1_HUMAN (82-823): 7.22e-13: 74.6: 12.64		KCC2A_HUMAN (15-321): 1.8e-46: 176: 32.48
+	Ce
		104748 G5EC35_CAEEL (192-791): 3.35e-09: 63.1: 9.67		KCC2D_CAEEL (13-341): 9.85e-48: 184: 31.42