Protein: PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

Gene: PCMD2, PCMTD2
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9NV79

Gene Ontology (top 5):
GO:0004719 - protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0005737 - cytoplasm
GO:0036211 - protein modification process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1371880

CUL5
Cullin-5

5

6

Small-scale

0.656

High

1450301

RBX2
RING-box protein 2

2

1

High-throughput

0.601

High

1450303

SEPT3
Neuronal-specific septin-3

2

1

High-throughput

0.558

High

1147291

ELOB
Elongin-B

2

1

Small-scale

0.533

High

243081

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.515

High

246159

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.515

High

791767

SYUA
Alpha-synuclein

1

1

High-throughput

0.515

High

927575

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

713135

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.493

High

1123840

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.493

High

335191

ARI2
E3 ubiquitin-protein ligase ARIH2

1

3

High-throughput

0.479

High

799509

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

1033794

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1155822

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

109519

G5E9A7
DM1 locus, WD repeat containing

1

2

High-throughput

0.470

High

822880

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.470

High

1096242

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.470

High

1279769

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

1066034

VAC14
Protein VAC14 homolog

1

2

High-throughput

0.439

High

1151092

PCH2
Pachytene checkpoint protein 2 homolog

1

2

High-throughput

0.439

High

971163

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1012268

RT11
Small ribosomal subunit protein uS11m

1

2

High-throughput

0.437

High

1031562

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1113000

CUL2
Cullin-2

1

6

Small-scale

0.437

High

1271229

DPPA4
Developmental pluripotency-associated protein 4

1

1

High-throughput

0.437

High

1412826

PCGF1
Polycomb group RING finger protein 1

1

4

High-throughput

0.437

High

1437222

NANOG
Homeobox protein NANOG

1

3

High-throughput

0.437

High

1450302

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

High-throughput

0.437

High

958719

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.426

High

430416

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

1450304

ACSL6
Long-chain-fatty-acid--CoA ligase 6

2

0

High-throughput

0.316

High

943455

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

High-throughput

0.282

High

1446643

AT132
Polyamine-transporting ATPase 13A2

1

0

Small-scale

0.282

High

867454

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

47423

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

216831

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.268

Low

1360760

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1450305

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

106724

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1147135

ELOC
Elongin-C

1

0

Small-scale

0.249

Low

1450306

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.249

Low

344336

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025