HitPredict

Interactor 1: STING (Q3TBT3)
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)
Gene: Sting1

Interactor 2: DDX41 (Q91VN6)
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41)
Gene: DDX41

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	21892174, 23142775
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0035458 - cellular response to interferon-beta GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051607 - defense response to virus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 378 Mm			1 622
+	Mm
		1110717 STING_MOUSE (1-378): 0: 595: 100.00		DDX3X_MOUSE (17-592): 4.35e-147: 442: 29.85
+	Mm
		1111015 STING_MOUSE (1-378): 0: 595: 100.00		Q8BTS0_MOUSE (88-569): 1.31e-146: 439: 32.85
+	Mm
		1110913 STING_MOUSE (1-378): 0: 595: 100.00		DDX42_MOUSE (8-620): 3.93e-142: 438: 31.88