HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: FZR1 (Q9R1K5)
Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)
Gene: FZR1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32434143
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0016567 - protein ubiquitination
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1140 Mm			1 493
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (300-493): 7.33e-56: 191: 19.49
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (299-493): 7.06e-53: 183: 18.88
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (8-339): 3.05e-51: 179: 14.78
+	Hs
		1082453 DDB1_HUMAN (1-1140): 0: 1445: 99.65		FZR1_HUMAN (319-492): 5.23e-19: 91.5: 19.55
+	Hs
		921580 DDB1_HUMAN (1-1140): 0: 1445: 99.65		GBB2_HUMAN (329-478): 9.4e-15: 77.4: 18.07
+	Hs
		560882 DDB1_HUMAN (1-1140): 0: 1445: 99.65		GBB3_HUMAN (349-479): 3.1e-14: 75.8: 20.59
+	Hs
		1073094 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (340-493): 9.46e-31: 128: 16.77
+	Hs
		1073186 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FZR1_HUMAN (319-492): 5.23e-19: 91.5: 19.55
+	Hs
		1073168 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		NLE1_HUMAN (3-174): 3.44e-13: 73.4: 13.37
+	Hs
		1014222 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		FZR1_HUMAN (319-492): 5.23e-19: 91.5: 19.55
+	Hs
		1014208 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		NLE1_HUMAN (3-174): 3.44e-13: 73.4: 13.37
+	Hs
		1014128 CPSF1_HUMAN (4-527): 1.42e-116: 396: 16.01		TAF5_HUMAN (232-472): 4.99e-09: 60.8: 23.14