Protein: PWP1
Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502)

Gene: PWP1
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q13610

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0005730 - nucleolus
GO:0005794 - Golgi apparatus
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1112283

CUL4A
Cullin-4A

5

20

Small-scale

0.709

High

975677

RL7A
Large ribosomal subunit protein eL8

1

12

High-throughput

0.691

High

446993

NPM
Nucleophosmin

3

6

High-throughput

0.656

High

872306

SOX2
Transcription factor SOX-2

3

20

High-throughput

0.656

High

1112318

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

11

High-throughput

0.647

High

960710

RL15
Large ribosomal subunit protein eL15

2

5

High-throughput

0.628

High

1091392

ANK3
Ankyrin-3

2

4

High-throughput

0.628

High

1038433

TIE2
Angiopoietin-1 receptor

1

10

High-throughput

0.618

High

194179

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.618

High

926351

BLM
RecQ-like DNA helicase BLM

1

20

Small-scale

0.618

High

970463

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

12

High-throughput

0.618

High

998292

H31
Histone H3.1

1

17

High-throughput

0.618

High

1016838

H33
Histone H3.3

1

17

High-throughput

0.618

High

1112290

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.618

High

1112294

DDB1
DNA damage-binding protein 1

1

17

Small-scale

0.618

High

1112320

FBXW7
F-box/WD repeat-containing protein 7

1

17

Small-scale

0.618

High

1112332

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

14

High-throughput

0.618

High

1112344

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

12

High-throughput

0.618

High

134026

IPO5
Importin-5

2

8

High-throughput

0.611

High

1112295

IF16
Gamma-interferon-inducible protein 16

2

3

High-throughput

0.611

High

643825

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

5

High-throughput

0.588

High

241617

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

1112296

LARP7
La-related protein 7

2

14

High-throughput

0.584

High

1110956

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.575

High

1112347

PP13
Galactoside-binding soluble lectin 13

2

7

High-throughput

0.574

High

396064

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1112316

ESR2
Estrogen receptor beta

2

20

High-throughput

0.571

High

1112337

LN28A
Protein lin-28 homolog A

2

5

High-throughput

0.571

High

1112284

CUL4B
Cullin-4B

1

20

Small-scale

0.561

High

1112353

DCAF1
DDB1- and CUL4-associated factor 1

1

17

Small-scale

0.561

High

157339

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.553

High

543449

PSG2
Pregnancy-specific beta-1-glycoprotein 2

1

3

Small-scale

0.553

High

640162

EPHA1
Ephrin type-A receptor 1

1

9

High-throughput

0.553

High

720213

UFO
Tyrosine-protein kinase receptor UFO

1

15

High-throughput

0.553

High

931945

EPHB4
Ephrin type-B receptor 4

1

9

High-throughput

0.553

High

1112300

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.553

High

1112301

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.553

High

1112330

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.553

High

1112339

RC3H2
Roquin-2

1

11

High-throughput

0.553

High

1112341

ANLN
Anillin

1

6

High-throughput

0.553

High

214506

HXA3
Homeobox protein Hox-A3

1

13

High-throughput

0.541

High

659678

NFYA
Nuclear transcription factor Y subunit alpha

1

1

High-throughput

0.541

High

920437

DAPK1
Death-associated protein kinase 1

1

7

High-throughput

0.536

High

354972

CHK2
Serine/threonine-protein kinase Chk2

1

12

High-throughput

0.536

High

479415

SRP19
Signal recognition particle 19 kDa protein

1

1

High-throughput

0.536

High

548993

KPSH1
Serine/threonine-protein kinase H1

1

5

High-throughput

0.536

High

833103

MNDA
Myeloid cell nuclear differentiation antigen

1

3

High-throughput

0.536

High

1006383

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.536

High

1112281

CUL1
Cullin-1

1

20

High-throughput

0.536

High

1112282

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1112285

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

High-throughput

0.536

High

1112293

NEDD8
Ubiquitin-like protein NEDD8

1

6

High-throughput

0.536

High

1112302

CSN6
COP9 signalosome complex subunit 6

1

2

High-throughput

0.536

High

1112305

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

15

High-throughput

0.536

High

1112306

TSYL5
Testis-specific Y-encoded-like protein 5

1

4

High-throughput

0.536

High

1112317

CSN5
COP9 signalosome complex subunit 5

1

6

High-throughput

0.536

High

1112327

SRPK1
SRSF protein kinase 1

1

18

High-throughput

0.536

High

1112351

SRPK3
SRSF protein kinase 3

1

20

High-throughput

0.536

High

1112352

DRG1
Developmentally-regulated GTP-binding protein 1

1

7

High-throughput

0.536

High

345778

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

11

High-throughput

0.533

High

1112292

PTPRR
Receptor-type tyrosine-protein phosphatase R

2

2

High-throughput

0.521

High

185677

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

14

High-throughput

0.501

High

422071

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

239951

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.500

High

129062

MEN1
Menin

1

3

High-throughput

0.479

High

140906

NOP56
Nucleolar protein 56

1

9

Small-scale

0.479

High

144263

ACACB
Acetyl-CoA carboxylase 2

1

14

High-throughput

0.479

High

224995

TLX3
T-cell leukemia homeobox protein 3

1

13

High-throughput

0.479

High

226548

TLX2
T-cell leukemia homeobox protein 2

1

7

High-throughput

0.479

High

247886

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

248294

HBP1
HMG box-containing protein 1

1

20

High-throughput

0.479

High

272148

OBSL1
Obscurin-like protein 1

1

8

High-throughput

0.479

High

319746

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

335120

ARI2
E3 ubiquitin-protein ligase ARIH2

1

14

High-throughput

0.479

High

363249

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.479

High

371969

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

400798

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

404041

GCR
Glucocorticoid receptor

1

20

Small-scale

0.479

High

406152

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

413791

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

472716

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

535032

BIP
Endoplasmic reticulum chaperone BiP

1

19

Small-scale

0.479

High

620347

NUCL
Nucleolin

1

4

High-throughput

0.479

High

637500

FLNA
Filamin-A

1

13

High-throughput

0.479

High

655817

TBG1
Tubulin gamma-1 chain

1

20

High-throughput

0.479

High

675492

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.479

High

711121

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

3

High-throughput

0.479

High

738978

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

761220

RYK
Tyrosine-protein kinase RYK

1

16

High-throughput

0.479

High

778064

VGFR2
Vascular endothelial growth factor receptor 2

1

8

High-throughput

0.479

High

786592

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

9

High-throughput

0.479

High

832519

ETV3
ETS translocation variant 3

1

17

High-throughput

0.479

High

837044

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

877511

LHX1
LIM/homeobox protein Lhx1

1

3

High-throughput

0.479

High

895711

LHX2
LIM/homeobox protein Lhx2

1

3

High-throughput

0.479

High

897263

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.479

High

899885

FXR1
RNA-binding protein FXR1

1

9

High-throughput

0.479

High

904686

MECP2
Methyl-CpG-binding protein 2

1

8

High-throughput

0.479

High

937743

FOXA1
Hepatocyte nuclear factor 3-alpha

1

9

High-throughput

0.479

High

964924

WDR5
WD repeat-containing protein 5

1

17

Small-scale

0.479

High

978916

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.479

High

1028128

IRF9
Interferon regulatory factor 9

1

1

High-throughput

0.479

High

1048500

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.479

High

1052865

HME1
Homeobox protein engrailed-1

1

4

High-throughput

0.479

High

1057455

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.479

High

1067296

EP300
Histone acetyltransferase p300

1

13

High-throughput

0.479

High

1112286

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

1112287

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1112288

STAT4
Signal transducer and activator of transcription 4

1

7

High-throughput

0.479

High

1112289

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

8

High-throughput

0.479

High

1112291

KIF14
Kinesin-like protein KIF14

1

12

High-throughput

0.479

High

1112297

HABP4
Intracellular hyaluronan-binding protein 4

1

4

High-throughput

0.479

High

1112303

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

1112310

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1112311

CGAS
Cyclic GMP-AMP synthase

1

2

High-throughput

0.479

High

1112312

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

1112313

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

1112314

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1112319

LHX4
LIM/homeobox protein Lhx4

1

3

High-throughput

0.479

High

1112321

TRI11
E3 ubiquitin-protein ligase TRIM11

1

2

Small-scale

0.479

High

1112323

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1112326

RANB9
Ran-binding protein 9

1

9

High-throughput

0.479

High

1112328

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1112329

KLF6
Krueppel-like factor 6

1

20

High-throughput

0.479

High

1112331

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

1112335

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1112336

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1112340

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

1112342

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

1112343

LYAR
Cell growth-regulating nucleolar protein

1

4

High-throughput

0.479

High

1112345

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

16

High-throughput

0.479

High

1112346

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1112348

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1112350

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.479

High

1112356

RBM8A
RNA-binding protein 8A

1

8

High-throughput

0.479

High

1112322

PRR11
Proline-rich protein 11

1

0

High-throughput

0.458

High

429851

JUN
Transcription factor Jun

1

15

High-throughput

0.445

High

952153

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

5

High-throughput

0.445

High

1112324

CI072
Guanine nucleotide exchange factor C9orf72

1

4

Small-scale

0.445

High

1112333

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

5

High-throughput

0.445

High

339740

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.437

High

350593

TXD12
Thioredoxin domain-containing protein 12

1

2

High-throughput

0.437

High

609997

VGFR1
Vascular endothelial growth factor receptor 1

1

7

High-throughput

0.437

High

641590

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

11

High-throughput

0.437

High

675022

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.437

High

711886

LTK
Leukocyte tyrosine kinase receptor

1

14

High-throughput

0.437

High

732307

PRDX2
Peroxiredoxin-2

1

8

High-throughput

0.437

High

787015

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

7

High-throughput

0.437

High

879064

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

12

High-throughput

0.437

High

991022

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

High-throughput

0.437

High

1107691

SQSTM
Sequestosome-1

1

8

High-throughput

0.437

High

1112298

RC3H1
Roquin-1

1

3

High-throughput

0.437

High

1112304

ZCH18
Zinc finger CCCH domain-containing protein 18

1

19

High-throughput

0.437

High

1112308

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

1112309

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

2

High-throughput

0.437

High

1112325

LMTK3
Serine/threonine-protein kinase LMTK3

1

18

High-throughput

0.437

High

1112349

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1112355

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.437

High

1112299

TENS2
Tensin-2

1

8

High-throughput

0.417

High

1112315

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

4

High-throughput

0.417

High

327996

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

5

High-throughput

0.407

High

1112334

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

1

High-throughput

0.407

High

1112354

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.328

High

1112307

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

692954

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

1112338

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025