HitPredict

Interactor 1: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Interactor 2: MEF2A (Q60929)
Myocyte-specific enhancer factor 2A
Gene: MEF2A

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21233771, 10737771
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1115 Mm			1 498
+	Mm
		1112770 Q3UJF1_MOUSE (1-1115): 0: 796: 100.00		MEF2C_MOUSE (1-498): 5.43e-89: 282: 57.96
+	Hs
		987234 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15
+	Mm
		1112760 Q3UJF1_MOUSE (1-1115): 0: 796: 100.00		MEF2D_MOUSE (1-496): 7.35e-71: 236: 50.47
+	Hs
		968805 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96
+	Mm
		1144403 HDAC5_MOUSE (1-1115): 0: 788: 99.28		MEF2D_MOUSE (1-496): 7.35e-71: 236: 50.47
+	Hs
		1059602 HDAC5_HUMAN (1-1115): 0: 760: 94.49		MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37
+	Mm
		1157743 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2C_MOUSE (1-498): 5.43e-89: 282: 57.96
+	Mm
		1141851 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2A_MOUSE (1-498): 7.41e-86: 275: 100.00
+	Hs
		880693 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15
+	Hs
		880686 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96
+	Mm
		1144399 HDAC4_MOUSE (3-1096): 0: 709: 54.56		MEF2D_MOUSE (1-496): 7.35e-71: 236: 50.47
+	Hs
		880729 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2D_HUMAN (1-496): 4.69e-72: 239: 50.37
+	Rn
		292567 HDAC4_RAT (3-1096): 0: 704: 54.56		MEF2D_RAT (1-496): 5.63e-66: 223: 49.91
+	Hs
		987233 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15
+	Hs
		968804 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96
+	Hs
		880687 HDAC4_HUMAN (3-1095): 0: 697: 55.51		MEF2B_HUMAN (1-224): 5.47e-63: 211: 46.96
+	Hs
		968817 HDAC9_HUMAN (26-1048): 0: 641: 55.03		MEF2B_HUMAN (1-224): 5.47e-63: 211: 46.96
+	Hs
		987223 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		MEF2C_HUMAN (1-498): 7.03e-88: 279: 58.15
+	Hs
		968793 HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82		MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96
+	Hs
		968777 HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70		MEF2A_HUMAN (1-498): 4.28e-83: 268: 88.96