Protein: RN114
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)

Gene: RN114, RNF114
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9Y508

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919918

UB2D2
Ubiquitin-conjugating enzyme E2 D2

6

20

Small-scale

0.951

High

476632

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

20

Small-scale

0.930

High

849499

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.929

High

1238411

DTX3
Probable E3 ubiquitin-protein ligase DTX3

3

3

High-throughput

0.861

High

1377919

RN114
E3 ubiquitin-protein ligase RNF114

3

18

Small-scale

0.845

High

1283436

RN166
E3 ubiquitin-protein ligase RNF166

2

19

High-throughput

0.811

High

851914

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

Small-scale

0.800

High

895969

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.800

High

896402

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.783

High

1151556

XAF1
XIAP-associated factor 1

6

6

Small-scale

0.739

High

718362

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.698

High

909395

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

1138933

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1282369

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

High-throughput

0.698

High

1283614

TRI52
E3 ubiquitin-protein ligase TRIM52

1

18

High-throughput

0.698

High

1284902

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1297384

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

High-throughput

0.698

High

1317549

TRI55
Tripartite motif-containing protein 55

1

18

High-throughput

0.698

High

1377872

TRAF6
TNF receptor-associated factor 6

1

20

High-throughput

0.698

High

1344071

PAR11
Protein mono-ADP-ribosyltransferase PARP11

4

14

High-throughput

0.697

High

599755

TNAP3
Tumor necrosis factor alpha-induced protein 3

3

17

Small-scale

0.683

High

1377468

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.656

High

932604

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

High-throughput

0.647

High

1315649

IDI2
Isopentenyl-diphosphate delta-isomerase 2

3

0

High-throughput

0.634

High

1327872

PAR12
Protein mono-ADP-ribosyltransferase PARP12

2

14

High-throughput

0.628

High

1343029

C1QR1
Complement component C1q receptor

2

3

High-throughput

0.628

High

229171

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

669104

PML
Protein PML

1

20

High-throughput

0.618

High

1304216

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.618

High

1345055

UBQL4
Ubiquilin-4

1

20

Small-scale

0.618

High

240817

USO1
General vesicular transport factor p115

2

10

High-throughput

0.611

High

1189109

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

2

14

High-throughput

0.611

High

1354997

ZRAN1
Ubiquitin thioesterase ZRANB1

2

19

High-throughput

0.584

High

502718

BIP
Endoplasmic reticulum chaperone BiP

1

16

Small-scale

0.561

High

445598

RSSA
Small ribosomal subunit protein uS2

1

3

High-throughput

0.541

High

1313393

TRAF4
TNF receptor-associated factor 4

1

18

High-throughput

0.541

High

1314609

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

13

High-throughput

0.541

High

1327692

RNF38
E3 ubiquitin-protein ligase RNF38

1

7

High-throughput

0.541

High

1377922

KAD5
Adenylate kinase isoenzyme 5

1

1

High-throughput

0.541

High

206665

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.536

High

658616

HXD10
Homeobox protein Hox-D10

1

11

High-throughput

0.536

High

738713

TNR3
Tumor necrosis factor receptor superfamily member 3

1

20

High-throughput

0.536

High

1139815

PLPP4
Phospholipid phosphatase 4

1

2

High-throughput

0.536

High

1343853

ANLN
Anillin

1

4

High-throughput

0.536

High

72172

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

1218669

U2D2L
Putative ubiquitin-conjugating enzyme E2 D2-like protein

1

20

High-throughput

0.528

High

905308

1433G
14-3-3 protein gamma

1

16

High-throughput

0.515

High

1065765

SETB1
Histone-lysine N-methyltransferase SETDB1

1

8

High-throughput

0.515

High

1251498

LMO3
LIM domain only protein 3

1

9

High-throughput

0.515

High

1273547

KAT5
Histone acetyltransferase KAT5

1

2

High-throughput

0.515

High

888316

MYPR
Myelin proteolipid protein

1

0

High-throughput

0.513

High

1192969

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.513

High

1377920

RAI2
Retinoic acid-induced protein 2

1

0

High-throughput

0.513

High

647715

MK03
Mitogen-activated protein kinase 3

1

3

High-throughput

0.508

High

1028458

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

15

Small-scale

0.501

High

1336134

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

11

Small-scale

0.501

High

1220114

UEVLD
Ubiquitin-conjugating enzyme E2 variant 3

1

7

High-throughput

0.494

High

351663

GLHA
Glycoprotein hormones alpha chain

1

1

High-throughput

0.489

High

503255

PPAL
Lysosomal acid phosphatase

1

1

High-throughput

0.489

High

949081

HTRA4
Serine protease HTRA4

1

3

High-throughput

0.489

High

1299918

CC85A
Coiled-coil domain-containing protein 85A

1

3

High-throughput

0.489

High

183179

KDM6A
Lysine-specific demethylase 6A

1

6

Small-scale

0.479

High

197434

SERA
D-3-phosphoglycerate dehydrogenase

1

2

Small-scale

0.479

High

245134

BRD4
Bromodomain-containing protein 4

1

9

High-throughput

0.479

High

626300

APC
Adenomatous polyposis coli protein

1

10

Small-scale

0.479

High

758372

CDN1A
Cyclin-dependent kinase inhibitor 1

1

3

Small-scale

0.479

High

836121

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.479

High

868826

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

928543

DYL1
Dynein light chain 1, cytoplasmic

1

4

Small-scale

0.479

High

967532

EWS
RNA-binding protein EWS

1

6

High-throughput

0.479

High

1037031

SQSTM
Sequestosome-1

1

15

High-throughput

0.479

High

1042930

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1063709

SUZ12
Polycomb protein SUZ12

1

3

High-throughput

0.479

High

1120930

PAR10
Protein mono-ADP-ribosyltransferase PARP10

1

14

Small-scale

0.479

High

1327726

SHRPN
Sharpin

1

8

Small-scale

0.479

High

1331732

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.479

High

1343411

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

8

Small-scale

0.479

High

265151

MAF
Transcription factor Maf

1

0

Small-scale

0.458

High

1190139

MAVS
Mitochondrial antiviral-signaling protein

1

18

Small-scale

0.437

High

1175

SIM26
Small integral membrane protein 26

1

1

High-throughput

0.407

High

1377921

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

3

0

High-throughput

0.347

High

611704

EVI2A
Protein EVI2A

1

0

High-throughput

0.282

High

1326962

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024