HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: ZER1 (Q7Z7L7)
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein) (Zyg11b-like protein)
Gene: ZER1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17304241, 18187417
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031462 - Cul2-RING ubiquitin ligase complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 766
+	Hs
		1114918 CUL4A_HUMAN (4-745): 0: 770: 26.86		ZER1_HUMAN (1-766): 0: 923: 100.00
+	Hs
		1112984 CUL2_HUMAN (1-745): 0: 839: 100.00		ZY11B_HUMAN (1-755): 0: 668: 26.58
+	Ce
		1164797 CUL2_CAEEL (2-745): 0: 718: 42.27		ZER1_CAEEL (147-760): 0: 619: 37.20
+	Ce
		1164788 CUL1_CAEEL (4-745): 0: 709: 30.76		ZER1_CAEEL (147-760): 0: 619: 37.20
+	Ce
		638829 CUL2_CAEEL (2-745): 0: 718: 42.27		ZYG11_CAEEL (77-733): 4.91e-170: 511: 22.45
+	Ce
		1164801 CUL2_CAEEL (2-745): 0: 718: 42.27		Q9XTS0_CAEEL (77-712): 2.09e-153: 465: 12.58
+	Ce
		114994 CUL2_CAEEL (2-745): 0: 718: 42.27		H2KMM0_CAEEL (109-710): 1.73e-126: 401: 14.58