Protein: ZY11B
Protein zyg-11 homolog B

Gene: ZY11B, ZYG11B
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9C0D3

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1112984

CUL2
Cullin-2

3

7

Small-scale

0.671

High

1421074

CLC11
C-type lectin domain family 11 member A

4

0

High-throughput

0.661

High

1356767

HDAC7
Histone deacetylase 7

3

0

High-throughput

0.638

High

1421072

TSP50
Probable threonine protease PRSS50

3

0

High-throughput

0.638

High

1234521

MRM1
rRNA methyltransferase 1, mitochondrial

4

1

High-throughput

0.630

High

1421060

ZY11B
Protein zyg-11 homolog B

1

1

Small-scale

0.625

High

303189

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.611

High

1390532

CDCA5
Sororin

2

1

High-throughput

0.611

High

60874

COLL1
Colipase-like protein 1

3

1

High-throughput

0.609

High

1279975

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.602

High

1421073

ASC
Apoptosis-associated speck-like protein containing a CARD

2

0

High-throughput

0.602

High

1147268

ELOB
Elongin-B

2

2

Small-scale

0.586

High

1094413

CSN1
COP9 signalosome complex subunit 1

2

0

High-throughput

0.576

High

1416534

HINT2
Adenosine 5'-monophosphoramidase HINT2

2

0

High-throughput

0.576

High

1338046

WFDC9
Protein WFDC9

2

1

High-throughput

0.574

High

260702

CUTA
Protein CutA

2

1

High-throughput

0.549

High

1350883

HUMMR
Protein MGARP

2

1

High-throughput

0.549

High

474966

VIME
Vimentin

1

1

High-throughput

0.536

High

1336396

SLAI1
SLAIN motif-containing protein 1

1

1

High-throughput

0.536

High

1421067

ZN701
Zinc finger protein 701

2

2

Small-scale

0.527

High

1386569

OPTN
Optineurin

1

1

High-throughput

0.515

High

564343

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

1132638

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

1154924

NEDD8
Ubiquitin-like protein NEDD8

1

0

High-throughput

0.513

High

1272552

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

1288245

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

1355892

GRK7
Rhodopsin kinase GRK7

1

0

High-throughput

0.513

High

1370357

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

1381279

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1147120

ELOC
Elongin-C

1

5

Small-scale

0.508

High

1352425

SH3R2
E3 ubiquitin-protein ligase SH3RF2

1

0

High-throughput

0.493

High

1127679

KT33B
Keratin, type I cuticular Ha3-II

1

3

High-throughput

0.489

High

1132186

HLX
H2.0-like homeobox protein

1

1

High-throughput

0.489

High

1207857

CLU1O
Putative uncharacterized protein CLLU1-AS1

1

1

High-throughput

0.489

High

1216689

CROCC
Rootletin

1

1

High-throughput

0.489

High

1294773

PTH
Peptidyl-tRNA hydrolase

1

1

High-throughput

0.489

High

1317109

TENS4
Tensin-4

1

1

High-throughput

0.489

High

1397271

TAFA4
Chemokine-like protein TAFA-4

1

2

High-throughput

0.489

High

1421062

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

1

High-throughput

0.489

High

1421076

NGN3
Neurogenin-3

1

1

High-throughput

0.489

High

1255435

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1421075

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

1390243

GIMA5
GTPase IMAP family member 5

1

1

Small-scale

0.471

High

580692

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

799462

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

869083

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

1101189

CLN3
Battenin

1

0

High-throughput

0.458

High

1421065

IFT46
Intraflagellar transport protein 46 homolog

1

0

Small-scale

0.458

High

1421066

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.458

High

1421071

DPOG2
DNA polymerase subunit gamma-2

1

1

High-throughput

0.445

High

75582

B3KSW4
Regulator of G protein signaling 20

1

1

High-throughput

0.407

High

587207

ITF2
Transcription factor 4

1

1

High-throughput

0.407

High

1178673

ISX
Intestine-specific homeobox

1

1

High-throughput

0.407

High

1351645

TCP1L
T-complex protein 10A homolog 1

1

1

High-throughput

0.407

High

1353719

MOT10
Monocarboxylate transporter 10

1

1

High-throughput

0.407

High

628647

CAP7
Azurocidin

4

0

High-throughput

0.360

High

1187682

T10IP
Testis-specific protein 10-interacting protein

4

0

High-throughput

0.360

High

1335600

GLBL3
Beta-galactosidase-1-like protein 3

3

0

High-throughput

0.347

High

1421068

NECP2
Adaptin ear-binding coat-associated protein 2

3

0

High-throughput

0.347

High

295766

AP1G2
AP-1 complex subunit gamma-like 2

2

0

High-throughput

0.328

High

587363

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

0

High-throughput

0.328

High

1287490

TRPT1
tRNA 2'-phosphotransferase 1

2

0

High-throughput

0.328

High

1309074

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

0

High-throughput

0.328

High

1364927

AP3S1
AP-3 complex subunit sigma-1

2

0

High-throughput

0.328

High

1395286

LCOR
Ligand-dependent corepressor

2

0

High-throughput

0.328

High

1421064

AT131
Endoplasmic reticulum transmembrane helix translocase

2

0

High-throughput

0.328

High

1398203

PPM1M
Protein phosphatase 1M

2

0

High-throughput

0.324

High

249313

G137B
Integral membrane protein GPR137B

2

0

High-throughput

0.318

High

1290266

Q86V94
LOC554223 protein

2

0

High-throughput

0.318

High

1363837

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

0

High-throughput

0.316

High

1323715

THEM5
Acyl-coenzyme A thioesterase THEM5

2

0

High-throughput

0.313

High

1421061

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.313

High

1421063

B2L12
Bcl-2-like protein 12

2

0

High-throughput

0.313

High

49543

SHSA3
Protein shisa-3 homolog

1

0

High-throughput

0.279

Low

133128

FOXE1
Forkhead box protein E1

1

0

High-throughput

0.279

Low

253894

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

472205

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

820578

GPV
Platelet glycoprotein V

1

0

High-throughput

0.279

Low

928749

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

High-throughput

0.279

Low

1105556

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

1121015

VGLL4
Transcription cofactor vestigial-like protein 4

1

0

High-throughput

0.279

Low

1133411

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

0

High-throughput

0.279

Low

1192206

AMZ1
Archaemetzincin-1

1

0

High-throughput

0.279

Low

1207029

CI152
Uncharacterized protein C9orf152

1

0

High-throughput

0.279

Low

1281394

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low

1293447

CQ082
Putative uncharacterized protein LINC02875

1

0

High-throughput

0.279

Low

1326691

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1329153

DB125
Beta-defensin 125

1

0

High-throughput

0.279

Low

1384568

NACC2
Nucleus accumbens-associated protein 2

1

0

High-throughput

0.279

Low

1397312

CMIP5
Ciliary microtubule inner protein 5

1

0

High-throughput

0.279

Low

1412634

PIMRE
Protein PIMREG

1

0

High-throughput

0.279

Low

1416154

SSBP4
Single-stranded DNA-binding protein 4

1

0

High-throughput

0.279

Low

1416774

RFIP5
Rab11 family-interacting protein 5

1

0

High-throughput

0.279

Low

1421069

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

0

High-throughput

0.279

Low

1421078

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.279

Low

106612

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

406618

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

412576

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

530975

CO7
Complement component C7

1

0

High-throughput

0.249

Low

957507

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.249

Low

1116296

PTC1
Protein patched homolog 1

1

0

Small-scale

0.249

Low

689996

CNTFR
Ciliary neurotrophic factor receptor subunit alpha

1

0

High-throughput

0.232

Low

870452

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

0

High-throughput

0.232

Low

1359777

ITLN2
Intelectin-2

1

0

High-throughput

0.232

Low

1421070

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.232

Low

1421077

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025