Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2
Interactor 2: FBXW5 (Q969U6)
F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5)
Gene: FBXW5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~F-box-like |
| Common GO terms | GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
