HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: SPT13 (Q5DU57)
Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)
Gene: Spata13

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1730 Mm			1 656
+	Mm
		1115959 SHAN3_MOUSE (1-1730): 0: 626: 100.00		BCR_MOUSE (14-529): 8.83e-90: 306: 17.59
+	Hs
		1049728 SHAN3_HUMAN (1-1730): 0: 601: 95.21		ARHG7_HUMAN (3-653): 9.38e-98: 319: 18.74
+	Mm
		1116136 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ARHG7_MOUSE (101-653): 7.64e-81: 275: 20.29
+	Mm
		1116034 SHAN3_MOUSE (1-1730): 0: 626: 100.00		NGEF_MOUSE (3-649): 3.12e-81: 273: 13.51
+	Hs
		1078902 SHAN3_HUMAN (1-1730): 0: 601: 95.21		ITSN1_HUMAN (72-617): 6.67e-84: 290: 16.67
+	Rn
		223053 SHAN3_RAT (1-1730): 0: 618: 98.39		ARHG7_RAT (149-653): 1.86e-77: 261: 20.75
+	Mm
		57847 SHAN3_MOUSE (1-1730): 0: 626: 100.00		KALRN_MOUSE (228-635): 5.32e-60: 220: 20.34
+	Hs
		1049744 SHAN2_HUMAN (8-1727): 2.64e-135: 466: 40.52		ARHG7_HUMAN (3-653): 9.38e-98: 319: 18.74
+	Hs
		506657 TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16		BCR_HUMAN (21-521): 1.32e-89: 305: 17.20
+	Rn
		223054 SHAN2_RAT (352-1727): 7.52e-89: 322: 35.92		ARHG7_RAT (149-653): 1.86e-77: 261: 20.75
+	Hs
		506579 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		BCR_HUMAN (21-521): 1.32e-89: 305: 17.20
+	Hs
		1021479 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		FARP1_HUMAN (13-626): 4.58e-82: 281: 16.75
+	Hs
		1330900 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		FARP1_HUMAN (13-626): 4.58e-82: 281: 16.75
+	Hs
		883686 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		FARP1_HUMAN (13-626): 4.58e-82: 281: 16.75
+	Hs
		299289 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		FARP2_HUMAN (66-590): 8.86e-78: 269: 18.35
+	Hs
		299252 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		FARP2_HUMAN (66-590): 8.86e-78: 269: 18.35
+	Hs
		1078859 MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66		ITSN1_HUMAN (72-617): 6.67e-84: 290: 16.67
+	Hs
		167038 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		PKHG1_HUMAN (193-656): 2.82e-79: 276: 23.29
+	Hs
		965179 ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64		FARP1_HUMAN (13-626): 4.58e-82: 281: 16.75
+	Rn
		223055 SHAN1_RAT (367-1725): 1.25e-27: 124: 14.14		ARHG7_RAT (149-653): 1.86e-77: 261: 20.75