HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: DLGP2 (Q8BJ42)
Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2)
Gene: Dlgap2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GKAP~PDZ_6
Common GO terms GO:0005886 - plasma membrane
GO:0043197 - dendritic spine
GO:0050804 - modulation of chemical synaptic transmission
GO:0098978 - glutamatergic synapse
GO:0099092 - postsynaptic density, intracellular component
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1730
Mm

1 1059
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Last updated: 15 Jul 2024