HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: TXTP (Q8JZU2)
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)
Gene: Slc25a1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	29111324, 28469556
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1730 Mm			1 311
+	Mm
		851088 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ADT2_MOUSE (119-310): 3.66e-37: 136: 24.02
+	Mm
		1116121 SHAN3_MOUSE (1-1730): 0: 626: 100.00		GHC2_MOUSE (29-278): 1.44e-33: 127: 32.25
+	Mm
		1116117 SHAN3_MOUSE (1-1730): 0: 626: 100.00		GHC1_MOUSE (21-282): 5.26e-27: 109: 28.43
+	Mm
		1116000 SHAN3_MOUSE (1-1730): 0: 626: 100.00		S2512_MOUSE (224-307): 5e-21: 95.3: 31.87
+	Mm
		1113678 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ADT4_MOUSE (216-311): 3.54e-13: 70.6: 19.42
+	Hs
		858329 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		TXTP_HUMAN (17-311): 7.68e-105: 310: 95.25
+	Hs
		858215 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		TXTP_HUMAN (17-311): 7.68e-105: 310: 95.25
+	Hs
		397507 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ADT2_HUMAN (121-310): 1.66e-37: 136: 24.26
+	Hs
		397329 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ADT2_HUMAN (121-310): 1.66e-37: 136: 24.26
+	Hs
		518487 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ADT3_HUMAN (121-310): 1.47e-36: 134: 22.77
+	Hs
		518299 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ADT3_HUMAN (121-310): 1.47e-36: 134: 22.77
+	Hs
		1309835 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ODC_HUMAN (17-308): 1.24e-29: 115: 29.30
+	Hs
		883624 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ODC_HUMAN (17-308): 1.24e-29: 115: 29.30
+	Hs
		1330849 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		GHC1_HUMAN (21-282): 1.31e-27: 111: 28.77
+	Hs
		883644 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		GHC1_HUMAN (21-282): 1.31e-27: 111: 28.77
+	Hs
		1021471 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		S2513_HUMAN (224-307): 8.51e-20: 91.8: 30.77
+	Hs
		274627 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		S2512_HUMAN (224-307): 1.14e-20: 94.1: 30.77
+	Hs
		274519 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		S2512_HUMAN (224-307): 1.14e-20: 94.1: 30.77
+	Hs
		1330875 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		S2513_HUMAN (224-307): 8.51e-20: 91.8: 30.77
+	Hs
		883665 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		S2513_HUMAN (224-307): 8.51e-20: 91.8: 30.77