Protein: PCLO
Protein piccolo (Aczonin)

Gene: PCLO
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9Y6V0

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005522 - profilin binding
GO:0005544 - calcium-dependent phospholipid binding
GO:0005856 - cytoskeleton
GO:0007010 - cytoskeleton organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

791885

SYUA
Alpha-synuclein

2

4

High-throughput

0.586

High

1117543

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.586

High

1288961

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

18

High-throughput

0.575

High

1490985

GIT1
ARF GTPase-activating protein GIT1

1

12

Small-scale

0.573

High

571698

HCLS1
Hematopoietic lineage cell-specific protein

1

4

High-throughput

0.553

High

1116183

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.536

High

299455

FLOT1
Flotillin-1

1

2

High-throughput

0.515

High

1122467

GIT2
ARF GTPase-activating protein GIT2

1

15

Small-scale

0.481

High

158047

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

177134

ERC2
ERC protein 2

1

15

Small-scale

0.479

High

243457

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

272583

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.479

High

346577

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.479

High

785563

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.479

High

946945

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

1033338

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1103484

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.479

High

1163322

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.479

High

1208916

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.479

High

1220920

RN123
E3 ubiquitin-protein ligase RNF123

1

6

High-throughput

0.479

High

1335128

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1367725

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

1372356

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.479

High

1408007

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.479

High

1408075

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

1490963

TR150
Thyroid hormone receptor-associated protein 3

1

7

High-throughput

0.479

High

280383

SC22B
Vesicle-trafficking protein SEC22b

1

1

High-throughput

0.470

High

426603

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.470

High

601927

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.470

High

1037461

H11
Histone H1.1

1

15

High-throughput

0.470

High

844242

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.458

High

979388

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

1448417

DUOX2
Dual oxidase 2

1

0

High-throughput

0.458

High

1461071

TNIK
TRAF2 and NCK-interacting protein kinase

1

11

High-throughput

0.457

High

255343

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

11

High-throughput

0.445

High

106948

APRIO
Alternative prion protein

1

7

High-throughput

0.437

High

138357

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.437

High

257024

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.437

High

331456

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.437

High

449810

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.437

High

659962

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.437

High

943436

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.437

High

1036036

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.437

High

1049219

RON
Macrophage-stimulating protein receptor

1

12

High-throughput

0.437

High

1141128

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.437

High

1271238

DPPA4
Developmental pluripotency-associated protein 4

1

1

High-throughput

0.437

High

1281388

DPPA2
Developmental pluripotency-associated protein 2

1

1

High-throughput

0.437

High

1324007

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.437

High

1325542

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.437

High

1406887

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

12

High-throughput

0.437

High

1432575

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

14

Small-scale

0.437

High

1454220

CEP72
Centrosomal protein of 72 kDa

1

1

High-throughput

0.437

High

1135519

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

320199

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

353659

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

361677

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.249

Low

566893

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

1149660

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.249

Low

1405795

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.249

Low

143497

E2F3
Transcription factor E2F3

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025