HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: IQEC1 (Q8R0S2)
IQ motif and SEC7 domain-containing protein 1
Gene: Iqsec1

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	27507650, 28671696, 28469556
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse GO:0099092 - postsynaptic density, intracellular component
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 961
+	Hs
		1150556 SHAN3_HUMAN (1-1730): 0: 601: 95.21		IQEC1_HUMAN (1-961): 0: 1169: 95.64
+	Mm
		1115908 SHAN3_MOUSE (1-1730): 0: 626: 100.00		IQEC2_MOUSE (19-956): 0: 861: 58.81
+	Hs
		1150559 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		IQEC1_HUMAN (1-961): 0: 1169: 95.64
+	Hs
		883536 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		IQEC1_HUMAN (1-961): 0: 1169: 95.64
+	Hs
		166950 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		IQEC1_HUMAN (1-961): 0: 1169: 95.64
+	Hs
		1266553 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		GBF1_HUMAN (324-722): 6.8e-91: 320: 22.69
+	Hs
		883585 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		GBF1_HUMAN (324-722): 6.8e-91: 320: 22.69
+	Hs
		212310 ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64		CYH3_HUMAN (512-861): 9.64e-101: 323: 28.34
+	Hs
		965143 ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64		PSD2_HUMAN (248-737): 6.46e-92: 310: 20.92