HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: SGIP1 (Q8VD37)
SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein)
Gene: SGIP1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1730 Mm			1 806
+	Mm
		292327 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ZAN_MOUSE (88-721): 2.39e-23: 109: 10.64
+	Mm
		88456 SHAN3_MOUSE (1-1730): 0: 626: 100.00		D3Z656_MOUSE (247-694): 8.06e-19: 94.1: 11.58
+	Mm
		93248 SHAN3_MOUSE (1-1730): 0: 626: 100.00		E9PWQ7_MOUSE (155-730): 1.87e-18: 93.4: 10.13
+	Mm
		1115904 SHAN3_MOUSE (1-1730): 0: 626: 100.00		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Hs
		979984 SHAN3_HUMAN (1-1730): 0: 601: 95.21		IF4G1_HUMAN (89-566): 8.02e-21: 100: 11.47
+	Mm
		1116160 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PCLO_MOUSE (6-528): 1.81e-11: 70.6: 9.00
+	Rn
		1337545 SHAN3_RAT (1-1730): 0: 618: 98.39		SHAN3_RAT (123-467): 1.53e-13: 77.1: 16.85
+	Mm
		936894 SHAN3_MOUSE (1-1730): 0: 626: 100.00		NACAM_MOUSE (14-735): 3.21e-09: 62.9: 10.74
+	Mm
		1115957 CSKI1_MOUSE (55-1397): 7.52e-114: 397: 15.53		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Mm
		103609 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		MICA3_MOUSE (7-595): 3.11e-31: 134: 12.94
+	Mm
		1115992 SHAN2_MOUSE (352-1727): 1.03e-90: 328: 35.55		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Mm
		103600 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Hs
		1021422 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		MICA3_HUMAN (8-553): 1.47e-24: 112: 13.01
+	Hs
		1295406 EHMT1_HUMAN (78-376): 2.2e-74: 275: 24.75		CHAP1_HUMAN (5-399): 5.93e-11: 68.3: 9.09
+	Hs
		1001573 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		FCHO2_HUMAN (2-351): 3.22e-12: 72.2: 28.34
+	Dm
		1361443 Q9VAU5_DROME (149-873): 9.98e-65: 246: 10.69		Q9VLS7_DROME (5-499): 1.6e-09: 64.1: 10.10
+	Hs
		1001587 MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66		FCHO2_HUMAN (2-351): 3.22e-12: 72.2: 28.34
+	Mm
		1115906 ANR28_MOUSE (224-592): 3.46e-43: 174: 14.32		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70
+	Dm
		1182373 Q7KU92_DROME (177-544): 6.44e-41: 169: 14.95		Q9VLS7_DROME (5-499): 1.6e-09: 64.1: 10.10
+	Mm
		88368 SHAN1_MOUSE (367-1725): 5.86e-28: 126: 14.36		SHAN3_MOUSE (123-467): 1.14e-13: 77.4: 17.70