Protein: SEPT9
Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1)

Gene: SEPT9, SEPTIN9
Organism: Homo sapiens
Interactions: 216
UniProt ID: Q9UHD8

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1121205

SEPT6
Septin-6

10

19

Small-scale

0.977

High

1156433

SEPT7
Septin-7

9

20

Small-scale

0.971

High

1137025

SEPT2
Septin-2

7

19

Small-scale

0.965

High

1450365

SEP11
Septin-11

6

19

Small-scale

0.944

High

1459673

SEPT3
Neuronal-specific septin-3

4

20

High-throughput

0.903

High

1361617

SEPT1
Septin-1

4

19

High-throughput

0.897

High

1454084

SEP10
Septin-10

3

20

High-throughput

0.861

High

1256432

SEP14
Septin-14

2

19

Small-scale

0.798

High

1365297

SEPT8
Septin-8

2

19

Small-scale

0.789

High

1459864

SEPT9
Septin-9

2

20

Small-scale

0.768

High

1432842

BORG4
Cdc42 effector protein 4

5

15

High-throughput

0.712

High

1161426

HIF1A
Hypoxia-inducible factor 1-alpha

5

1

Small-scale

0.709

High

1406712

SEPT5
Septin-5

1

20

High-throughput

0.691

High

1060304

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

4

1

High-throughput

0.683

High

1447400

ANLN
Anillin

3

11

High-throughput

0.656

High

243216

PRKN
E3 ubiquitin-protein ligase parkin

3

11

High-throughput

0.640

High

1384290

SH3K1
SH3 domain-containing kinase-binding protein 1

2

7

Small-scale

0.619

High

839185

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

1

High-throughput

0.601

High

376062

RASK
GTPase KRas

2

20

High-throughput

0.584

High

564512

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.584

High

1446994

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

1

Small-scale

0.584

High

914794

RM12
Large ribosomal subunit protein bL12m

2

9

High-throughput

0.574

High

935251

TERA
Transitional endoplasmic reticulum ATPase

2

5

High-throughput

0.571

High

123869

MYO1C
Unconventional myosin-Ic

1

7

Small-scale

0.561

High

1459867

MYO6
Unconventional myosin-VI

1

2

Small-scale

0.561

High

1459873

NEMO
NF-kappa-B essential modulator

1

5

High-throughput

0.561

High

1152286

MARE1
Microtubule-associated protein RP/EB family member 1

2

0

Small-scale

0.559

High

1359462

LMO7
LIM domain only protein 7

2

0

Small-scale

0.559

High

269413

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.553

High

530526

TAU
Microtubule-associated protein tau

2

14

High-throughput

0.552

High

535645

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.536

High

1399439

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.536

High

1454155

ARP3B
Actin-related protein 3B

1

3

High-throughput

0.536

High

106801

APRIO
Alternative prion protein

2

8

High-throughput

0.533

High

1145932

RBP1
RalA-binding protein 1

2

4

High-throughput

0.521

High

1154469

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.518

High

1432032

TAOK3
Serine/threonine-protein kinase TAO3

1

4

High-throughput

0.515

High

1109414

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.513

High

1404480

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

423402

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

861826

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.501

High

389553

FINC
Fibronectin

1

4

High-throughput

0.489

High

1111341

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

1432600

CPVL
Probable serine carboxypeptidase CPVL

1

4

High-throughput

0.489

High

920336

PLK1
Serine/threonine-protein kinase PLK1

1

0

Small-scale

0.480

High

124125

SNP23
Synaptosomal-associated protein 23

1

3

Small-scale

0.479

High

171347

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

3

Small-scale

0.479

High

173511

XPO1
Exportin-1

1

13

High-throughput

0.479

High

224824

ACTN4
Alpha-actinin-4

1

1

Small-scale

0.479

High

227996

MYO1B
Unconventional myosin-Ib

1

8

Small-scale

0.479

High

248130

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

259166

DNJA2
DnaJ homolog subfamily A member 2

1

4

High-throughput

0.479

High

272531

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

340258

PCNT
Pericentrin

1

10

High-throughput

0.479

High

346457

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.479

High

363982

EGFR
Epidermal growth factor receptor

1

17

High-throughput

0.479

High

373421

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

374261

RASN
GTPase NRas

1

20

High-throughput

0.479

High

374991

RASH
GTPase HRas

1

19

High-throughput

0.479

High

401661

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

414789

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

459788

PROF1
Profilin-1

1

1

Small-scale

0.479

High

463822

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

475051

VIME
Vimentin

1

1

Small-scale

0.479

High

520718

RRAS
Ras-related protein R-Ras

1

20

Small-scale

0.479

High

556401

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

580718

AMPN
Aminopeptidase N

1

1

Small-scale

0.479

High

583010

EZRI
Ezrin

1

3

High-throughput

0.479

High

603382

KPCA
Protein kinase C alpha type

1

1

Small-scale

0.479

High

607195

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

643124

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

644592

TENX
Tenascin-X

1

3

Small-scale

0.479

High

714497

PML
Protein PML

1

5

High-throughput

0.479

High

715830

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

767511

RADI
Radixin

1

3

High-throughput

0.479

High

791806

SYUA
Alpha-synuclein

1

7

High-throughput

0.479

High

799551

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.479

High

831597

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

891859

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

955725

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

995877

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

1008929

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

1045876

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1094649

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.479

High

1095836

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

8

High-throughput

0.479

High

1116100

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

1120842

DSG2
Desmoglein-2

1

3

High-throughput

0.479

High

1121361

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

1140996

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1153026

MYLK
Myosin light chain kinase, smooth muscle

1

1

Small-scale

0.479

High

1156890

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1208078

CYTSB
Cytospin-B

1

4

High-throughput

0.479

High

1217575

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

2

High-throughput

0.479

High

1218998

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

1225099

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

4

High-throughput

0.479

High

1250797

MPRIP
Myosin phosphatase Rho-interacting protein

1

4

Small-scale

0.479

High

1253243

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

1255976

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1258407

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

1292887

STING
Stimulator of interferon genes protein

1

2

Small-scale

0.479

High

1313503

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1336321

LS14A
Protein LSM14 homolog A

1

1

Small-scale

0.479

High

1350492

BICD2
Protein bicaudal D homolog 2

1

7

High-throughput

0.479

High

1364656

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1368185

HDAC2
Histone deacetylase 2

1

4

High-throughput

0.479

High

1385401

ARMC5
Armadillo repeat-containing protein 5

1

1

High-throughput

0.479

High

1394204

LRCH3
DISP complex protein LRCH3

1

7

High-throughput

0.479

High

1396980

IFT74
Intraflagellar transport protein 74 homolog

1

8

High-throughput

0.479

High

1400347

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1417085

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

1420985

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1434162

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1446841

TRI36
E3 ubiquitin-protein ligase TRIM36

1

15

High-throughput

0.479

High

1451306

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

1453543

PD1L1
Programmed cell death 1 ligand 1

1

2

Small-scale

0.479

High

1453792

RAI14
Ankycorbin

1

4

High-throughput

0.479

High

1459205

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1459742

LIMA1
LIM domain and actin-binding protein 1

1

3

Small-scale

0.479

High

1459865

XPO7
Exportin-7

1

13

High-throughput

0.479

High

1459866

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

1459871

TRAF6
TNF receptor-associated factor 6

1

5

High-throughput

0.479

High

1459872

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

2

High-throughput

0.479

High

1417801

LRRC3
Leucine-rich repeat-containing protein 3

1

4

High-throughput

0.470

High

168574

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

0

High-throughput

0.458

High

183372

ZN185
Zinc finger protein 185

1

0

Small-scale

0.458

High

476057

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

0

Small-scale

0.458

High

630079

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

773300

MYH10
Myosin-10

1

0

Small-scale

0.458

High

911423

IMA5
Importin subunit alpha-5

1

0

Small-scale

0.458

High

1041354

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

1138725

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1144910

RASA2
Ras GTPase-activating protein 2

1

0

Small-scale

0.458

High

1220869

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1239754

PPR18
Phostensin

1

0

Small-scale

0.458

High

1247034

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1288289

LYRIC
Protein LYRIC

1

0

Small-scale

0.458

High

1315146

EXOC8
Exocyst complex component 8

1

0

Small-scale

0.458

High

1370439

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1390828

CPNE2
Copine-2

1

0

Small-scale

0.458

High

1411960

PELO
Protein pelota homolog

1

0

High-throughput

0.458

High

1420253

UBXN6
UBX domain-containing protein 6

1

0

Small-scale

0.458

High

1431336

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1450558

FANCI
Fanconi anemia group I protein

1

0

Small-scale

0.458

High

1454724

RBM27
RNA-binding protein 27

1

0

Small-scale

0.458

High

890695

RGS3
Regulator of G-protein signaling 3

1

9

High-throughput

0.445

High

1209767

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1120378

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

High-throughput

0.439

High

157956

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

285512

EED
Polycomb protein EED

1

2

High-throughput

0.437

High

299420

FLOT1
Flotillin-1

1

4

High-throughput

0.437

High

324230

CE152
Centrosomal protein of 152 kDa

1

2

High-throughput

0.437

High

353611

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

412762

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

427952

ICAM1
Intercellular adhesion molecule 1

1

3

Small-scale

0.437

High

472361

CFAH
Complement factor H

1

1

Small-scale

0.437

High

487857

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.437

High

541743

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.437

High

589968

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

648716

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

685760

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

High-throughput

0.437

High

696791

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

710912

EPHB2
Ephrin type-B receptor 2

1

14

High-throughput

0.437

High

769442

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

851436

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.437

High

898018

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.437

High

965309

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1100500

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

1104691

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.437

High

1138144

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.437

High

1155877

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

1226554

DCA15
DDB1- and CUL4-associated factor 15

1

3

High-throughput

0.437

High

1229124

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.437

High

1229747

VIR
Protein virilizer homolog

1

4

High-throughput

0.437

High

1251521

CD109
CD109 antigen

1

1

Small-scale

0.437

High

1276922

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1288603

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.437

High

1289693

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.437

High

1338419

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

1363886

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.437

High

1367518

ESR2
Estrogen receptor beta

1

12

High-throughput

0.437

High

1416478

LS14B
Protein LSM14 homolog B

1

1

Small-scale

0.437

High

1432297

ZN106
Zinc finger protein 106

1

2

Small-scale

0.437

High

1433067

CA198
Uncharacterized protein C1orf198

1

1

High-throughput

0.437

High

1459868

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.437

High

1459869

SRRM2
Serine/arginine repetitive matrix protein 2

1

4

High-throughput

0.437

High

994856

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.426

High

1332525

POC5
Centrosomal protein POC5

1

0

Small-scale

0.426

High

158348

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.407

High

344355

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.407

High

442960

PRGR
Progesterone receptor

1

11

Small-scale

0.407

High

773683

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.407

High

1130505

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.407

High

1434565

VIAAT
Vesicular inhibitory amino acid transporter

1

4

High-throughput

0.407

High

887303

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.373

High

522751

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

Small-scale

0.288

High

471309

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

1314293

NIM1
Serine/threonine-protein kinase NIM1

1

0

High-throughput

0.279

Low

1387683

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1415900

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

1446638

B3GA2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

1

0

High-throughput

0.269

Low

362075

AATM
Aspartate aminotransferase, mitochondrial

1

0

Small-scale

0.249

Low

569228

CD59
CD59 glycoprotein

1

0

Small-scale

0.249

Low

939662

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.249

Low

1194439

LARP7
La-related protein 7

1

0

High-throughput

0.249

Low

1251244

LIPI
Lipase member I

1

0

Small-scale

0.249

Low

1386299

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.249

Low

1418829

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.249

Low

1453020

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1458430

GBG12

1

0

Small-scale

0.249

Low

1459870

ICE1
Little elongation complex subunit 1

1

0

Small-scale

0.249

Low

62608

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

1103429

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

1292303

S2611
Sodium-independent sulfate anion transporter

1

0

High-throughput

0.232

Low

1330800

S35G3
Solute carrier family 35 member G3

1

0

High-throughput

0.232

Low

1392592

S41A3
Solute carrier family 41 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025