Interactor 1: THOC5 (Q13769)
THO complex subunit 5 (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90)
Gene: THOC5

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.745

The method score is based on:

Property Details
Experiments 26496610, 15998806, 17190602, 31839598, 40437099, 23222130, 19165146, 37020021, 23299939
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0003729 - mRNA binding
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 683
Hs

1 1593
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025