HitPredict

Interactor 1: PDS5B (Q4VA53)
Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)
Gene: PDS5B

Interactor 2: SMC1A (Q9CU62)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Chromosome segregation protein SmcB) (Sb1.8)
Gene: SMC1A

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21699228
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006281 - DNA repair GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1446 Mm			1 1233
+	Hs
		1057405 PDS5B_HUMAN (1-1419): 0: 1599: 96.83		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84
+	Hs
		1057273 PDS5A_HUMAN (2-1356): 0: 1512: 67.48		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84
+	Xl
		292728 PD5BA_XENLA (1-1446): 0: 1524: 84.36		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Mm
		93884 E9QPI5_MOUSE (2-1350): 0: 1506: 67.36		SMC1A_MOUSE (1-1233): 5.26e-126: 420: 100.00
+	Mm
		1149127 PDS5A_MOUSE (2-1350): 0: 1487: 67.06		SMC1A_MOUSE (1-1233): 5.26e-126: 420: 100.00
+	Xl
		292730 PD5AA_XENLA (4-1354): 0: 1479: 66.59		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Xl
		292729 PD5AB_XENLA (4-1354): 0: 1477: 66.67		SMC1A_XENLA (1-1232): 1.2e-119: 402: 93.99
+	Hs
		1345702 PDS5B_HUMAN (1-1419): 0: 1599: 96.83		SMC3_HUMAN (3-1229): 1.16e-69: 258: 16.17
+	Xl
		292740 PD5BB_XENLA (1-1445): 0: 1538: 83.80		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Xl
		292738 PD5BA_XENLA (1-1446): 0: 1524: 84.36		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Xl
		1115499 PD5BA_XENLA (1-1446): 0: 1524: 84.36		Q8AW91_XENLA (3-1229): 3.98e-69: 256: 15.90
+	Hs
		1100586 PDS5A_HUMAN (2-1356): 0: 1512: 67.48		SMC3_HUMAN (3-1229): 1.16e-69: 258: 16.17
+	Mm
		93885 E9QPI5_MOUSE (2-1350): 0: 1506: 67.36		SMC3_MOUSE (3-1229): 7.9e-70: 258: 16.17
+	Xl
		292739 PD5AA_XENLA (4-1354): 0: 1479: 66.59		SMC3_XENLA (3-1229): 1.8e-71: 263: 16.27
+	Xl
		1117310 PD5AB_XENLA (4-1354): 0: 1477: 66.67		Q8AW91_XENLA (3-1229): 3.98e-69: 256: 15.90
+	Sp
		293288 PDS5_SCHPO (12-1154): 0: 946: 22.51		SMC1_SCHPO (1-1225): 3.48e-71: 262: 32.77
+	Sp
		193880 PDS5_SCHPO (12-1154): 0: 946: 22.51		SMC3_SCHPO (3-1225): 1.24e-65: 245: 17.18
+	Sc
		810772 PDS5_YEAST (6-1178): 0: 877: 19.24		SMC3_YEAST (3-1215): 8.01e-78: 283: 18.28
+	Sc
		700799 PDS5_YEAST (6-1178): 0: 877: 19.24		SMC1_YEAST (1-1225): 8.93e-70: 258: 26.70
+	Hs
		69118 A9IYQ1_HUMAN (1047-1348): 1.93e-44: 165: 91.06		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84