Protein: T2H2L
General transcription factor IIH subunit 2-like protein (General transcription factor IIH polypeptide 2-like protein)

Gene: T2H2L, GTF2H2C;
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q6P1K8

Gene Ontology (top 5):
GO:0000439 - transcription factor TFIIH core complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
GO:0006351 - DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1118841

TF2H3
General transcription factor IIH subunit 3

5

3

High-throughput

0.931

High

744667

TF2H1
General transcription factor IIH subunit 1

4

2

Small-scale

0.895

High

622822

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

3

2

High-throughput

0.861

High

611676

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

4

High-throughput

0.740

High

1240796

TF2H4
General transcription factor IIH subunit 4

3

3

High-throughput

0.667

High

897310

CDK7
Cyclin-dependent kinase 7

3

2

High-throughput

0.643

High

1240792

TF2H5
General transcription factor IIH subunit 5

2

1

High-throughput

0.628

High

1118814

TF2H2
General transcription factor IIH subunit 2

2

3

High-throughput

0.584

High

1240793

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

0

High-throughput

0.549

High

137541

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

4

High-throughput

0.515

High

216465

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

1106343

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

1141177

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1240794

FA43A
Protein FAM43A

1

1

High-throughput

0.470

High

1240797

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

1

High-throughput

0.470

High

396336

ESR1
Estrogen receptor

1

3

High-throughput

0.445

High

908756

MAT1
CDK-activating kinase assembly factor MAT1

1

2

High-throughput

0.445

High

1240800

PRD11
PR domain-containing protein 11

1

1

High-throughput

0.445

High

172952

XPO1
Exportin-1

1

3

High-throughput

0.437

High

1240798

EAF1
ELL-associated factor 1

1

0

High-throughput

0.426

High

94500

D6RID8
GTF2H2 family member C

1

3

High-throughput

0.407

High

132488

CDC7
Cell division cycle 7-related protein kinase

1

1

High-throughput

0.407

High

1194658

CCD40
Coiled-coil domain-containing protein 40

1

1

High-throughput

0.407

High

1240795

DLRB2
Dynein light chain roadblock-type 2

1

1

High-throughput

0.407

High

932407

GALC
Galactocerebrosidase

3

0

High-throughput

0.347

High

1042582

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

3

0

High-throughput

0.347

High

1240799

HIRP3
HIRA-interacting protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025