HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 1190
+	Hs
		149386 CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		990854 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Mm
		1257595 AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11		PALS2_MOUSE (423-890): 7.01e-101: 332: 15.97
+	Hs
		990961 MRCKB_HUMAN (223-790): 7.52e-19: 95: 8.90		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		1021508 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		148718 CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		1118988 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Hs
		847099 SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59		PALS2_HUMAN (423-890): 8.19e-96: 318: 15.77
+	Hs
		1119004 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		DLG5_HUMAN (25-522): 2.43e-14: 80.4: 11.77
+	Mm
		1257596 AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11		PALS1_MOUSE (3-296): 9.91e-12: 71.3: 10.32
+	Hs
		1222245 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Mm
		936586 ROCK2_MOUSE (357-853): 4.34e-19: 95.7: 11.35		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		1232518 AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Mm
		823534 CTRO_MOUSE (533-855): 2.5e-11: 70.3: 11.15		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Rn
		92840 CTRO_RAT (533-855): 7.07e-11: 69.1: 11.15		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Mm
		1143486 RRBP1_MOUSE (149-759): 2.39e-10: 67.3: 9.98		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1322042 AMOL1_MOUSE (1-912): 1.67e-43: 173: 43.02		PALS1_MOUSE (3-296): 9.91e-12: 71.3: 10.32
+	Mm
		1225209 AMOL2_MOUSE (1-853): 8.67e-34: 142: 26.49		PALS1_MOUSE (3-296): 9.91e-12: 71.3: 10.32