HitPredict

Interactor 1: K9JA46 (K9JA46)
Heat shock protein HSP 90-alpha
Gene: EL52

Interactor 2: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 543
+	Hs
		431574 HS90A_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Hs
		437930 HS90B_HUMAN (19-732): 0: 1059: 86.13		STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00
+	Dm
		365481 HSP83_DROME (15-732): 0: 1034: 78.41		Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42
+	At
		878278 HS902_ARATH (15-732): 0: 982: 68.24		HSOP2_ARATH (3-543): 4.73e-97: 307: 41.86
+	Hs
		432195 HS90A_HUMAN (1-732): 0: 1087: 100.00		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		432268 HS90A_HUMAN (1-732): 0: 1087: 100.00		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		174556 HS90A_HUMAN (1-732): 0: 1087: 100.00		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		438464 HS90B_HUMAN (19-732): 0: 1059: 86.13		DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28
+	Hs
		297024 HS90A_HUMAN (1-732): 0: 1087: 100.00		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Hs
		431774 HS90A_HUMAN (1-732): 0: 1087: 100.00		SPAG1_HUMAN (405-527): 2.93e-11: 68.4: 14.63
+	Hs
		438533 HS90B_HUMAN (19-732): 0: 1059: 86.13		RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14
+	Hs
		174561 HS90B_HUMAN (19-732): 0: 1059: 86.13		OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57
+	Hs
		431797 HS90A_HUMAN (1-732): 0: 1087: 100.00		IFT88_HUMAN (4-150): 8.37e-09: 60.3: 12.93
+	Hs
		213451 HS90A_HUMAN (1-732): 0: 1087: 100.00		SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54
+	Hs
		297025 HS90B_HUMAN (19-732): 0: 1059: 86.13		TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00
+	Hs
		213454 HS90B_HUMAN (19-732): 0: 1059: 86.13		SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54
+	Ce
		183711 HSP90_CAEEL (14-732): 0: 960: 74.83		STIP1_CAEEL (2-280): 5.87e-13: 71.9: 13.24
+	Ca
		804535 HSP90_CANAL (12-732): 0: 914: 60.50		Q5ADP3_CANAL (1-178): 1.05e-12: 73: 8.12
+	Sc
		365568 HSP82_YEAST (16-732): 0: 907: 60.08		TOM70_YEAST (353-515): 2.09e-14: 78: 22.09
+	Sp
		784798 HSP90_SCHPO (15-732): 0: 914: 62.08		STI1_SCHPO (2-278): 8.15e-10: 63.4: 9.86