HitPredict

Interactor 1: K9JA46 (K9JA46)
Heat shock protein HSP 90-alpha
Gene: EL52

Interactor 2: CHRD1 (Q9UHD1)
Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana)
Gene: CHORDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CHORD~HSP90
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 332
+	Hs
		432333 HS90A_HUMAN (1-732): 0: 1087: 100.00		CHRD1_HUMAN (1-332): 4.52e-177: 495: 100.00
+	Mm
		432455 HS90A_MOUSE (1-732): 0: 1083: 97.82		CHRD1_MOUSE (1-328): 5.56e-174: 487: 96.34
+	Hs
		438592 HS90B_HUMAN (19-732): 0: 1059: 86.13		CHRD1_HUMAN (1-332): 4.52e-177: 495: 100.00
+	Mm
		513702 HS90B_MOUSE (19-732): 0: 1063: 86.98		CHRD1_MOUSE (1-328): 5.56e-174: 487: 96.34
+	Hs
		432350 HS90A_HUMAN (1-732): 0: 1087: 100.00		ITBP2_HUMAN (1-326): 6.98e-155: 439: 46.95
+	Mm
		432458 HS90A_MOUSE (1-732): 0: 1083: 97.82		ITBP2_MOUSE (1-326): 6.8e-155: 439: 48.33
+	Mm
		513706 HS90B_MOUSE (19-732): 0: 1063: 86.98		ITBP2_MOUSE (1-326): 6.8e-155: 439: 48.33
+	Hs
		438609 HS90B_HUMAN (19-732): 0: 1059: 86.13		ITBP2_HUMAN (1-326): 6.98e-155: 439: 46.95
+	Dm
		365474 HSP83_DROME (15-732): 0: 1034: 78.41		CHRD1_DROME (4-332): 5.64e-145: 414: 42.18
+	Hs
		432387 HS90A_HUMAN (1-732): 0: 1087: 100.00		SGT1_HUMAN (173-332): 1.99e-46: 162: 18.14
+	Hs
		438644 HS90B_HUMAN (19-732): 0: 1059: 86.13		SGT1_HUMAN (173-332): 1.99e-46: 162: 18.14
+	At
		646596 HS901_ARATH (15-732): 0: 981: 69.49		SGT1A_ARATH (220-332): 3.14e-39: 143: 24.78
+	At
		878286 HS902_ARATH (15-732): 0: 982: 68.24		SGT1B_ARATH (230-331): 1.21e-35: 134: 28.43
+	At
		646597 HS901_ARATH (15-732): 0: 981: 69.49		SGT1B_ARATH (230-331): 1.21e-35: 134: 28.43
+	At
		878285 HS902_ARATH (15-732): 0: 982: 68.24		RAR1_ARATH (157-229): 7.41e-17: 80.3: 36.99
+	At
		646595 HS901_ARATH (15-732): 0: 981: 69.49		RAR1_ARATH (157-229): 7.41e-17: 80.3: 36.99
+	Hs
		538450 ENPL_HUMAN (14-701): 0: 898: 46.78		SGT1_HUMAN (173-332): 1.99e-46: 162: 18.14
+	Sc
		367015 HSP82_YEAST (16-732): 0: 907: 60.08		SGT1_YEAST (213-329): 7.9e-27: 111: 22.14
+	Sc
		544530 HSC82_YEAST (16-732): 0: 902: 59.39		SGT1_YEAST (213-329): 7.9e-27: 111: 22.14