HitPredict

Interactor 1: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Interactor 2: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	27716508, 30190310
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 568 Hs			1 361
+	Hs
		1217464 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1049257 KEAP1_HUMAN (8-564): 2.73e-161: 475: 35.88		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		299523 KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		307194 KLHL2_HUMAN (13-567): 3.8e-158: 466: 41.36		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217446 KLH28_HUMAN (15-565): 1.89e-155: 458: 37.77		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217412 KLHL6_HUMAN (21-542): 7.38e-83: 272: 31.90		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217438 KLHL1_HUMAN (365-567): 7.55e-59: 210: 37.93		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217431 KLHL4_HUMAN (360-567): 9.8e-58: 207: 36.54		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1120805 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		NUDC1_HUMAN (155-282): 4.12e-26: 111: 20.93
+	Hs
		1217452 KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217450 KLHL9_HUMAN (380-568): 3.91e-43: 164: 27.55		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217403 KLH36_HUMAN (379-567): 1.6e-35: 143: 25.63		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1217455 KLHL3_HUMAN (422-568): 1.81e-34: 139: 36.05		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1153785 KLH10_HUMAN (428-568): 1.65e-33: 136: 33.80		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		152493 ENC1_HUMAN (378-568): 9.99e-32: 131: 21.29		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1264861 KLHL6_HUMAN (21-542): 7.38e-83: 272: 31.90		NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38
+	Hs
		1261421 KLHL1_HUMAN (365-567): 7.55e-59: 210: 37.93		NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11
+	Hs
		1261414 KLHL4_HUMAN (360-567): 9.8e-58: 207: 36.54		NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11
+	Hs
		1301408 KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06		NUDC1_HUMAN (155-282): 4.12e-26: 111: 20.93
+	Hs
		1188084 Q7Z350_HUMAN (380-568): 2.29e-43: 164: 27.55		NUDC1_HUMAN (155-282): 4.12e-26: 111: 20.93