HitPredict

Interactor 1: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Interactor 2: IPP (Q9Y573)
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)
Gene: IPP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 584
+	Hs
		1377325 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		IPP_HUMAN (1-584): 1.26e-175: 511: 100.00
+	Hs
		1120826 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLHL3_HUMAN (16-584): 3.18e-161: 474: 33.45
+	Hs
		1120821 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLHL9_HUMAN (4-584): 2.45e-149: 445: 25.68
+	Hs
		1120822 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH13_HUMAN (4-584): 1.47e-148: 444: 24.32
+	Dm
		980055 KELC_DROME (9-567): 1.41e-157: 489: 40.04		KELC_DROME (3-584): 7.3e-153: 477: 31.51
+	Hs
		1120769 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH24_HUMAN (1-584): 1.87e-144: 432: 26.41
+	Hs
		1164636 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		KLH24_HUMAN (1-584): 1.87e-144: 432: 26.41
+	Hs
		1120765 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH26_HUMAN (2-582): 3.26e-134: 406: 26.32
+	Hs
		1121511 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		KLH26_HUMAN (2-582): 3.26e-134: 406: 26.32
+	Hs
		307182 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLHL2_HUMAN (123-484): 4.64e-48: 178: 21.10
+	Hs
		1049221 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KEAP1_HUMAN (388-584): 1.25e-44: 169: 31.00
+	Hs
		1120764 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH12_HUMAN (9-438): 5.29e-40: 155: 18.14
+	Hs
		1120830 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH20_HUMAN (270-436): 2.67e-33: 136: 30.54
+	Hs
		1120768 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH17_HUMAN (275-436): 5.45e-32: 133: 28.40
+	Hs
		1377320 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		KLH20_HUMAN (270-436): 2.67e-33: 136: 30.54
+	Dm
		1374538 KLHDB_DROME (3-566): 3.83e-171: 500: 42.23		KLHDB_DROME (180-436): 7.24e-36: 144: 23.35
+	Mm
		1164599 KLH17_MOUSE (11-566): 1.56e-162: 479: 40.75		KLH17_MOUSE (275-436): 5.39e-32: 133: 28.40
+	Hs
		1120827 KLH12_HUMAN (1-568): 2.43e-180: 522: 100.00		KLH21_HUMAN (339-584): 2.35e-13: 74.7: 24.80
+	Hs
		1356007 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		KLH21_HUMAN (339-584): 2.35e-13: 74.7: 24.80