HitPredict

Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~SAM_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1655 Hs			1 723
+	Hs
		1122330 SCRIB_HUMAN (1-1655): 0: 940: 100.00		LGR4_HUMAN (5-321): 4.72e-43: 169: 16.91
+	Hs
		1122349 SCRIB_HUMAN (1-1655): 0: 940: 100.00		LRC40_HUMAN (30-251): 2.94e-16: 84.7: 18.60
+	Hs
		1122329 SCRIB_HUMAN (1-1655): 0: 940: 100.00		LRRC1_HUMAN (17-165): 1.96e-12: 72.4: 23.49
+	At
		88688 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		PEPR2_ARATH (1-382): 1.36e-50: 193: 14.46
+	At
		89570 FLS2_ARATH (8-622): 7.41e-105: 365: 21.33		ERL1_ARATH (116-544): 5.33e-51: 193: 14.22
+	At
		1425722 GSO2_ARATH (3-807): 5.16e-104: 365: 15.70		EMS1_ARATH (211-646): 2.14e-41: 165: 12.59
+	At
		88710 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		BRL2_ARATH (199-624): 1.49e-35: 146: 8.80
+	At
		88699 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		MIK1_ARATH (151-646): 2.22e-29: 127: 12.77
+	At
		88708 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		Q9XGZ2_ARATH (1-273): 1.47e-29: 127: 13.92
+	At
		88698 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		PXC2_ARATH (225-530): 5.02e-26: 116: 8.57
+	At
		88662 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		SKM1_ARATH (270-665): 6.98e-24: 109: 10.29
+	At
		88712 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		BRL1_ARATH (7-214): 9.7e-22: 102: 17.65
+	At
		88701 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		BAME2_ARATH (293-651): 9.11e-21: 99: 11.33
+	At
		88692 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		Y3804_ARATH (211-553): 1.28e-18: 92.9: 10.20
+	At
		88660 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		BAME1_ARATH (310-675): 7.91e-18: 90.3: 12.16
+	At
		88696 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		IRK_ARATH (344-618): 7.52e-18: 90.3: 15.47
+	At
		235820 GSO2_ARATH (3-807): 5.16e-104: 365: 15.70		BAME1_ARATH (310-675): 7.91e-18: 90.3: 12.16
+	At
		88667 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		ERECT_ARATH (407-546): 2.97e-12: 72.2: 18.57
+	At
		88649 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		RGI3_ARATH (388-625): 4.26e-10: 65.3: 10.79
+	At
		88652 GSO1_ARATH (1-553): 5.39e-107: 373: 24.41		Y4361_ARATH (401-625): 3.32e-09: 62.6: 11.07