Protein: FLS2
LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2) (Protein FLAGELLIN-SENSITIVE 2)

Gene: FLS2
Organism: Arabidopsis thaliana
Interactions: 64
UniProt ID: Q9FL28

Gene Ontology (top 5):
GO:0004675 - transmembrane receptor protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1376472

BAK1
BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1

18

20

Small-scale

0.986

High

235416

BIK1
Serine/threonine-protein kinase BIK1

3

4

Small-scale

0.900

High

1426154

FLS2
LRR receptor-like serine/threonine-protein kinase FLS2

4

20

Small-scale

0.884

High

88151

Y1699
Probable LRR receptor-like serine/threonine-protein kinase At1g69990

2

20

High-throughput

0.768

High

88767

GHR1
LRR receptor-like serine/threonine-protein kinase GHR1

2

19

High-throughput

0.768

High

89152

EFR
LRR receptor-like serine/threonine-protein kinase EFR

2

19

High-throughput

0.768

High

89570

ERL1
LRR receptor-like serine/threonine-protein kinase ERL1

2

19

High-throughput

0.768

High

89626

HSL2
LRR receptor-like serine/threonine-protein kinase HSL2

2

20

High-throughput

0.768

High

146888

Y1719
Probable inactive receptor kinase At1g27190

2

20

High-throughput

0.768

High

198428

O22178
non-specific serine/threonine protein kinase

2

20

High-throughput

0.768

High

235822

BAME1
Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1

2

20

High-throughput

0.768

High

1320586

SERK5
Somatic embryogenesis receptor kinase 5

2

20

High-throughput

0.768

High

1354661

Y4052
Probable LRR receptor-like serine/threonine-protein kinase At4g30520

2

20

High-throughput

0.768

High

1355635

Y5371
Probable LRR receptor-like serine/threonine-protein kinase At5g63710

2

20

High-throughput

0.768

High

1409065

Y5838
Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380

2

20

High-throughput

0.768

High

1422324

PSYR1
Tyrosine-sulfated glycopeptide receptor 1

2

19

High-throughput

0.768

High

1422733

SRF6
Protein STRUBBELIG-RECEPTOR FAMILY 6

2

20

High-throughput

0.768

High

1423204

Y1668
Probable inactive leucine-rich repeat receptor-like protein kinase At1g66830

2

20

High-throughput

0.768

High

1426157

NIK1
Protein NSP-INTERACTING KINASE 1

2

20

High-throughput

0.768

High

1426158

BRL3
Receptor-like protein kinase BRI1-like 3

2

20

High-throughput

0.768

High

1426159

Y1848
Probable inactive receptor kinase At1g48480

2

20

High-throughput

0.768

High

1426160

IRK
Probable LRR receptor-like serine/threonine-protein kinase IRK

2

20

High-throughput

0.768

High

1426165

Y1421
Putative inactive receptor-like protein kinase At1g64210

2

20

High-throughput

0.768

High

1426166

Q9SHU6
Leucine-rich repeat protein kinase family protein

2

20

High-throughput

0.768

High

1426167

SERK4
Somatic embryogenesis receptor kinase 4

2

20

High-throughput

0.768

High

1426173

Y2451
Leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14510

2

20

High-throughput

0.768

High

1426174

RPK1
Probable LRR receptor-like serine/threonine-protein kinase RPK1

2

20

High-throughput

0.768

High

1426176

BRL1
Serine/threonine-protein kinase BRI1-like 1

2

20

High-throughput

0.768

High

1426162

LRK62
L-type lectin-domain containing receptor kinase VI.2

1

20

Small-scale

0.747

High

1421675

CRK6
Cysteine-rich receptor-like protein kinase 6

1

20

Small-scale

0.724

High

1426161

CRK4
Cysteine-rich receptor-like protein kinase 4

1

20

Small-scale

0.724

High

1426172

CRK36
Cysteine-rich receptor-like protein kinase 36

1

20

Small-scale

0.724

High

1426171

Q9SVG8
Leucine-rich repeat protein kinase family protein

1

20

High-throughput

0.698

High

1250995

ERL2
LRR receptor-like serine/threonine-protein kinase ERL2

1

19

High-throughput

0.653

High

1426156

Y3359
Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At3g53590

1

20

High-throughput

0.653

High

1426163

MIK1
MDIS1-interacting receptor like kinase 1

1

20

High-throughput

0.653

High

1426168

PUB13
U-box domain-containing protein 13

2

1

Small-scale

0.653

High

101327

F4IVP3
Leucine-rich repeat protein kinase family protein

1

20

High-throughput

0.647

High

265677

RPS5
Disease resistance protein RPS5

1

3

Small-scale

0.647

High

1167991

UBQ3
Polyubiquitin 3 [Cleaved into: Ubiquitin]

1

5

Small-scale

0.647

High

1184663

RPM1
Disease resistance protein RPM1

1

3

Small-scale

0.647

High

1192641

RPS2
Disease resistance protein RPS2

1

3

Small-scale

0.647

High

1425308

BSK8
Serine/threonine-protein kinase BSK8

1

20

Small-scale

0.647

High

1041965

RBG7
Glycine-rich RNA-binding protein 7

1

1

Small-scale

0.640

High

854417

P2C70
Protein phosphatase 2C 70

1

3

Small-scale

0.621

High

100136

RLK7
Receptor-like protein kinase 7

1

20

High-throughput

0.618

High

103567

RGI4
Leucine-rich repeat receptor-like serine/threonine-protein kinase RGI4

1

19

High-throughput

0.618

High

265881

BAME3
Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3

1

20

High-throughput

0.618

High

1192463

ERECT
LRR receptor-like serine/threonine-protein kinase ERECTA

1

19

High-throughput

0.618

High

1299440

Q8GX94
Leucine-rich repeat protein kinase family protein

1

20

High-throughput

0.618

High

1374145

BSK1
Serine/threonine-protein kinase BSK1

1

20

Small-scale

0.618

High

1422675

IOS1
LRR receptor-like serine/threonine-protein kinase IOS1

1

20

High-throughput

0.618

High

1426164

RPK2
LRR receptor-like serine/threonine-protein kinase RPK2

1

20

High-throughput

0.618

High

1426175

Q9ZVD4
Leucine-rich repeat receptor-like protein kinase

1

20

High-throughput

0.618

High

265462

IQD6
Protein IQ-DOMAIN 6

1

8

High-throughput

0.541

High

1422085

CNIH1
Protein cornichon homolog 1

1

8

High-throughput

0.541

High

1318928

BETL2
Bet1-like protein At1g29060

1

8

High-throughput

0.494

High

1426155

ACA8
Calcium-transporting ATPase 8, plasma membrane-type

1

1

Small-scale

0.481

High

1300183

RIN4
RPM1-interacting protein 4

1

0

Small-scale

0.480

High

1426169

RTNLA
Reticulon-like protein B1

1

3

Small-scale

0.479

High

1426170

RTNLB
Reticulon-like protein B2

1

3

Small-scale

0.479

High

1285190

MORC1
Protein MICRORCHIDIA 1

1

0

Small-scale

0.458

High

1285226

RM16L
Putative ribosomal protein uL16-like, mitochondrial

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025