Interactor 1: PYDC2 (Q56P42)
Pyrin domain-containing protein 2 (Pyrin-only protein 2) (cellular POP2) (cPOP2)
Gene: PYDC2
Interactor 2: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.683 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17178784 |
| Identification Methods | pull down, anti tag coimmunoprecipitation, two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PYRIN~PYRIN |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0045087 - innate immune response GO:1901223 - negative regulation of non-canonical NF-kappaB signal transduction |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
