Protein: DPOA2
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)

Gene: DPOA2, POLA2
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q14181

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0005829 - cytosol
GO:0006260 - DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488007

DPOLA
DNA polymerase alpha catalytic subunit

2

10

Small-scale

0.768

High

1099670

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

0

High-throughput

0.736

High

885529

PRI1
DNA primase small subunit

2

3

High-throughput

0.628

High

192716

ARPC5
Actin-related protein 2/3 complex subunit 5

2

0

High-throughput

0.602

High

712206

TKT
Transketolase

2

0

High-throughput

0.602

High

988362

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.602

High

1122773

STN1
CST complex subunit STN1

2

0

High-throughput

0.602

High

1122739

EZH2
Histone-lysine N-methyltransferase EZH2

2

0

High-throughput

0.588

High

131062

TULP2
Tubby-related protein 2

2

1

High-throughput

0.574

High

1122758

SNX21
Sorting nexin-21

2

1

High-throughput

0.574

High

1122769

LRC27
Leucine-rich repeat-containing protein 27

2

1

High-throughput

0.574

High

487301

PARP1
Poly [ADP-ribose] polymerase 1

1

2

Small-scale

0.561

High

241659

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1007688

RAE1L
mRNA export factor RAE1

2

0

High-throughput

0.559

High

868690

LEG7
Galectin-7

2

1

High-throughput

0.558

High

938346

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.541

High

1122738

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.541

High

755916

MCM5
DNA replication licensing factor MCM5

1

6

High-throughput

0.536

High

1065191

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1122768

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1122750

ULK2
Serine/threonine-protein kinase ULK2

1

0

High-throughput

0.518

High

1122751

STK40
Serine/threonine-protein kinase 40

1

0

High-throughput

0.518

High

1122752

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.518

High

1122764

KLF6
Krueppel-like factor 6

1

0

High-throughput

0.518

High

1122771

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.518

High

1122775

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.518

High

731285

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.515

High

457090

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.513

High

629857

BTF3
Transcription factor BTF3

1

0

High-throughput

0.513

High

1122767

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.513

High

422095

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

885577

PRI2
DNA primase large subunit

1

2

Small-scale

0.501

High

1122770

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.494

High

1122774

AKTIP
AKT-interacting protein

1

1

High-throughput

0.494

High

280613

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

562052

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

884750

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

930885

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

937001

CASP6
Caspase-6

1

0

High-throughput

0.493

High

981490

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

1122783

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

290375

RFPL2
Ret finger protein-like 2

1

1

High-throughput

0.489

High

1122754

SSH3
Protein phosphatase Slingshot homolog 3

1

1

High-throughput

0.489

High

652513

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

0

High-throughput

0.486

High

1122748

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.486

High

1122778

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.486

High

1122753

HELB
DNA helicase B

1

0

Small-scale

0.480

High

172807

XPO1
Exportin-1

1

1

High-throughput

0.479

High

588675

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

695435

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

881522

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

980760

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1113083

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1114808

CUL4A
Cullin-4A

1

2

High-throughput

0.479

High

1115188

CUL4B
Cullin-4B

1

2

High-throughput

0.479

High

1122744

MCM10
Protein MCM10 homolog

1

2

High-throughput

0.479

High

1122747

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.479

High

1122756

ASB11
Ankyrin repeat and SOCS box protein 11

1

1

High-throughput

0.479

High

941160

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

259936

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

606756

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

768169

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

881920

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.458

High

995585

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1016847

H33
Histone H3.3

1

0

High-throughput

0.458

High

1033675

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1122741

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1122761

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1122763

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1122776

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1122777

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1122779

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1122781

HERC5
E3 ISG15--protein ligase HERC5

1

0

Small-scale

0.458

High

1122746

RBM23
Probable RNA-binding protein 23

1

1

High-throughput

0.439

High

1122766

HGH1
Protein HGH1 homolog

1

1

High-throughput

0.439

High

1102984

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

1122743

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1122745

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1122772

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1122780

XPO7
Exportin-7

1

1

High-throughput

0.437

High

529783

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

664868

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.426

High

1122742

Q6IA98
RNPC4 protein

1

3

High-throughput

0.417

High

1122759

Q96BK8
Protein HGH1 homolog

1

1

High-throughput

0.417

High

70893

ZBBX
Zinc finger B-box domain-containing protein 1

2

0

High-throughput

0.328

High

1122755

LIPH
Lipase member H

2

0

High-throughput

0.328

High

599112

CBPE
Carboxypeptidase E

1

0

High-throughput

0.282

High

609876

IBP3
Insulin-like growth factor-binding protein 3

1

0

High-throughput

0.282

High

650161

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.282

High

720474

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.282

High

784603

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.282

High

1121615

DHX34
Probable ATP-dependent RNA helicase DHX34

1

0

High-throughput

0.282

High

1122749

F219A
Protein FAM219A

1

0

High-throughput

0.282

High

1122760

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.282

High

1122784

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

0

High-throughput

0.279

Low

333473

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.279

Low

848258

MAGA3
Melanoma-associated antigen 3

1

0

High-throughput

0.279

Low

1041990

LMNB2
Lamin-B2

1

0

High-throughput

0.279

Low

1122762

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

1122765

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1122782

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

282585

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.268

Low

1081528

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

1122757

SFRP3
Secreted frizzled-related protein 3

1

0

High-throughput

0.265

Low

1122785

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.265

Low

302829

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

1122740

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025