Interactor 1: DOC2A (Q14183)
Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha)
Gene: DOC2A

Interactor 2: DOC2B (Q14184)
Double C2-like domain-containing protein beta (Doc2-beta)
Gene: DOC2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2
Common GO terms GO:0005544 - calcium-dependent phospholipid binding
GO:0045202 - synapse
GO:0045956 - positive regulation of calcium ion-dependent exocytosis
GO:0061669 - spontaneous neurotransmitter secretion
GO:0099502 - calcium-dependent activation of synaptic vesicle fusion
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 400
Hs

1 412
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Service provided by Combinatics, Japan

Last updated: 11Aug2025