HitPredict

Interactor 1: M9MRS9 (M9MRS9)
Formin homology 2 domain containing, isoform E
Gene: Fhos

Interactor 2: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24553290
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0030866 - cortical actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1387 Dm			1 192
+	Dm
		112307 M9MRS9_DROME (1-1387): 0: 1273: 100.00		RHO1_DROME (5-192): 2.35e-72: 218: 55.85
+	Hs
		925768 FHOD1_HUMAN (636-1373): 2.6e-126: 423: 38.25		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		925658 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67
+	Hs
		1330940 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32
+	Hs
		545645 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		545484 FMNL3_HUMAN (884-1361): 2.11e-125: 417: 17.83		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		894633 FHOD1_HUMAN (636-1373): 2.6e-126: 423: 38.25		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		951386 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19
+	Hs
		892621 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		894489 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		894190 FMNL3_HUMAN (884-1361): 2.11e-125: 417: 17.83		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		243089 DIAP2_HUMAN (878-1371): 3.87e-121: 407: 19.39		RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06
+	Hs
		900958 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		900661 FMNL3_HUMAN (884-1361): 2.11e-125: 417: 17.83		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		564704 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RHOQ_HUMAN (4-192): 9.76e-73: 220: 62.05
+	Hs
		436532 DIAP3_HUMAN (870-1379): 3.04e-125: 420: 18.51		RHOC_HUMAN (5-192): 2.38e-72: 218: 54.26
+	Hs
		243095 DIAP2_HUMAN (878-1371): 3.87e-121: 407: 19.39		RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53
+	Hs
		243096 DIAP2_HUMAN (878-1371): 3.87e-121: 407: 19.39		CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27
+	Hs
		243097 DIAP2_HUMAN (878-1371): 3.87e-121: 407: 19.39		RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79
+	Hs
		243091 DIAP2_HUMAN (878-1371): 3.87e-121: 407: 19.39		RHOQ_HUMAN (4-192): 9.76e-73: 220: 62.05