HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 512
+	Hs
		463316 MUC1_HUMAN (590-1353): 8.23e-94: 337: 14.16		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		557066 MUC1_HUMAN (590-1353): 8.23e-94: 337: 14.16		SRC_HUMAN (1-510): 0: 591: 51.97
+	Hs
		439935 MUC1_HUMAN (590-1353): 8.23e-94: 337: 14.16		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		463299 DMD_HUMAN (1575-3179): 8.64e-64: 246: 14.62		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		362149 MUC1_HUMAN (590-1353): 8.23e-94: 337: 14.16		ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88
+	Hs
		463457 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		463314 DESP_HUMAN (1529-3369): 2.49e-57: 224: 10.08		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		174692 SPTN2_HUMAN (1288-3070): 3.18e-54: 214: 14.77		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		440030 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		440078 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		463397 UTRN_HUMAN (1888-3400): 5.41e-47: 190: 9.85		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		439934 DESP_HUMAN (1529-3369): 2.49e-57: 224: 10.08		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		440337 DESP_HUMAN (1529-3369): 2.49e-57: 224: 10.08		FYN_HUMAN (1-510): 0: 583: 54.31
+	Hs
		174688 SPTN2_HUMAN (1288-3070): 3.18e-54: 214: 14.77		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		439991 UTRN_HUMAN (1888-3400): 5.41e-47: 190: 9.85		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		463510 SPTN1_HUMAN (2534-3501): 1.51e-33: 146: 13.02		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		440069 SPTN1_HUMAN (2534-3501): 1.51e-33: 146: 13.02		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		463842 MACF1_HUMAN (1966-3131): 2.32e-09: 66: 9.81		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		362286 SPTN1_HUMAN (2534-3501): 1.51e-33: 146: 13.02		ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88
+	Hs
		440243 MACF1_HUMAN (1966-3131): 2.32e-09: 66: 9.81		LCK_HUMAN (1-512): 0: 585: 63.62