HitPredict

Interactor 1: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Interactor 2: AGO1 (Q9UL18)
Protein argonaute-1 (Argonaute1) (hAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Putative RNA-binding protein Q99)
Gene: AGO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 857
+	Hs
		432356 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		432448 HS90A_MOUSE (96-271): 1.07e-44: 167: 50.85		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		438615 HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		432355 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Mm
		1174807 Q71LX8_MOUSE (96-256): 4.94e-41: 156: 51.85		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		1123461 H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		438614 HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		432271 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		438537 HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Hs
		432278 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Hs
		438545 HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85		AGO4_HUMAN (9-857): 0: 1167: 83.04
+	Dm
		365460 HSP83_DROME (96-256): 2.48e-43: 162: 52.15		Q32KD4_DROME (5-857): 0: 1153: 73.30
+	At
		138329 HS903_ARATH (96-256): 1.39e-42: 160: 49.08		AGO1_ARATH (2-856): 0: 1104: 41.65
+	Ce
		108540 ENPL1_CAEEL (93-409): 2.41e-34: 137: 22.88		G5EGR6_CAEEL (21-857): 0: 1109: 66.36
+	Hs
		432159 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		PIWL1_HUMAN (18-824): 0: 733: 22.22
+	Hs
		432088 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		PIWL2_HUMAN (5-819): 0: 709: 21.77
+	Dm
		365485 HSP83_DROME (96-256): 2.48e-43: 162: 52.15		AGO2_DROME (28-816): 0: 714: 32.09
+	Hs
		432003 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		PIWL4_HUMAN (18-820): 0: 675: 22.11
+	Dm
		365462 HSP83_DROME (96-256): 2.48e-43: 162: 52.15		AGO3_DROME (29-824): 0: 621: 21.23
+	Hs
		431946 HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41		Q5TA56_HUMAN (3-216): 4.03e-99: 309: 67.71