Protein: CHD7
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.-) (ATP-dependent helicase CHD7)

Gene: CHD7
Organism: Homo sapiens
Interactions: 158
UniProt ID: Q9P2D1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001501 - skeletal system development
GO:0001701 - in utero embryonic development
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1439224

CHD8
Chromodomain-helicase-DNA-binding protein 8

2

16

Small-scale

0.845

High

903506

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

2

19

Small-scale

0.789

High

980464

H4
Histone H4

2

13

High-throughput

0.754

High

998897

H31
Histone H3.1

2

20

High-throughput

0.754

High

1066525

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.691

High

1163254

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

872830

SOX2
Transcription factor SOX-2

4

20

Small-scale

0.686

High

487840

PARP1
Poly [ADP-ribose] polymerase 1

3

20

Small-scale

0.660

High

755011

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

883721

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

981151

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

1017264

H33
Histone H3.3

1

20

High-throughput

0.618

High

1097601

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.618

High

1145549

RBBP5
Retinoblastoma-binding protein 5

1

18

Small-scale

0.618

High

1384461

PF21A
PHD finger protein 21A

1

20

High-throughput

0.618

High

1436814

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.618

High

1454484

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

20

Small-scale

0.618

High

1347567

SMRC2
SWI/SNF complex subunit SMARCC2

2

20

Small-scale

0.611

High

1380028

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

20

Small-scale

0.611

High

373368

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

520414

ANDR
Androgen receptor

2

20

Small-scale

0.584

High

129816

CBX4
E3 SUMO-protein ligase CBX4

1

20

High-throughput

0.575

High

397115

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

401623

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

10

High-throughput

0.571

High

834372

GARS
Glycine--tRNA ligase

2

0

High-throughput

0.559

High

854358

KI67
Proliferation marker protein Ki-67

1

9

High-throughput

0.536

High

876652

NEST
Nestin

1

20

High-throughput

0.536

High

1111325

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.536

High

1144199

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1228285

ARID2
AT-rich interactive domain-containing protein 2

1

15

Small-scale

0.536

High

1288003

PB1
Protein polybromo-1

1

20

Small-scale

0.536

High

1370721

SMRC1
SWI/SNF complex subunit SMARCC1

1

17

Small-scale

0.536

High

1446407

BRD7
Bromodomain-containing protein 7

1

20

Small-scale

0.536

High

1454483

IKBL1
NF-kappa-B inhibitor-like protein 1

1

2

High-throughput

0.536

High

976001

RL7A
Large ribosomal subunit protein eL8

1

5

High-throughput

0.515

High

1434806

F124B
Protein FAM124B

1

1

Small-scale

0.515

High

1086714

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

6

Small-scale

0.500

High

1247682

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

11

Small-scale

0.500

High

1370761

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

11

Small-scale

0.500

High

1392074

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

11

Small-scale

0.500

High

1324491

AN36B
Ankyrin repeat domain-containing protein 36B

1

4

High-throughput

0.489

High

1407488

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.480

High

66851

DUXA
Double homeobox protein A

1

15

High-throughput

0.479

High

130641

SPT5H
Transcription elongation factor SPT5

1

8

High-throughput

0.479

High

143301

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

154767

ARI1A
AT-rich interactive domain-containing protein 1A

1

19

High-throughput

0.479

High

181572

TBXT
T-box transcription factor T

1

12

High-throughput

0.479

High

191140

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

210134

CRX
Cone-rod homeobox protein

1

16

High-throughput

0.479

High

225131

TLX3
T-cell leukemia homeobox protein 3

1

15

High-throughput

0.479

High

226614

TLX2
T-cell leukemia homeobox protein 2

1

8

High-throughput

0.479

High

247000

KDM1A
Lysine-specific histone demethylase 1A

1

20

High-throughput

0.479

High

317014

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.479

High

339880

KLF8
Krueppel-like factor 8

1

18

High-throughput

0.479

High

404499

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

406752

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

414757

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

444006

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

4

High-throughput

0.479

High

468867

HS90B
Heat shock protein HSP 90-beta

1

8

High-throughput

0.479

High

474341

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

519428

MYB
Transcriptional activator Myb

1

11

High-throughput

0.479

High

538483

EGR2
E3 SUMO-protein ligase EGR2

1

4

High-throughput

0.479

High

540960

ERG
Transcriptional regulator ERG

1

12

High-throughput

0.479

High

558459

XRCC6
X-ray repair cross-complementing protein 6

1

8

High-throughput

0.479

High

607175

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

630070

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

662289

PAX7
Paired box protein Pax-7

1

11

High-throughput

0.479

High

662511

GATA2
Endothelial transcription factor GATA-2

1

18

High-throughput

0.479

High

662663

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

18

High-throughput

0.479

High

675709

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.479

High

685368

PAX6
Paired box protein Pax-6

1

10

High-throughput

0.479

High

687881

SYVC
Valine--tRNA ligase

1

5

High-throughput

0.479

High

697280

APEX1
DNA repair nuclease/redox regulator APEX1

1

3

High-throughput

0.479

High

703209

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

725330

TLX1
T-cell leukemia homeobox protein 1

1

16

High-throughput

0.479

High

775925

HNF1B
Hepatocyte nuclear factor 1-beta

1

14

High-throughput

0.479

High

776139

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776259

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

800140

COIL
Coilin

1

7

High-throughput

0.479

High

832585

ETV3
ETS translocation variant 3

1

13

High-throughput

0.479

High

834075

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

837100

ELK3
ETS domain-containing protein Elk-3

1

14

High-throughput

0.479

High

851687

GATA4
Transcription factor GATA-4

1

18

High-throughput

0.479

High

851815

NKX21
Homeobox protein Nkx-2.1

1

18

High-throughput

0.479

High

873124

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

877571

LHX1
LIM/homeobox protein Lhx1

1

7

High-throughput

0.479

High

879561

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

18

High-throughput

0.479

High

887285

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.479

High

895809

LHX2
LIM/homeobox protein Lhx2

1

6

High-throughput

0.479

High

905228

MECP2
Methyl-CpG-binding protein 2

1

20

High-throughput

0.479

High

920327

PLK1
Serine/threonine-protein kinase PLK1

1

10

High-throughput

0.479

High

938513

PAX9
Paired box protein Pax-9

1

9

High-throughput

0.479

High

942126

SOX10
Transcription factor SOX-10

1

20

Small-scale

0.479

High

985930

RL11
Large ribosomal subunit protein uL5

1

4

High-throughput

0.479

High

986259

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.479

High

1024900

VIGLN
Vigilin

1

18

High-throughput

0.479

High

1033801

PO5F1
POU domain, class 5, transcription factor 1

1

13

High-throughput

0.479

High

1040086

PAX2
Paired box protein Pax-2

1

9

High-throughput

0.479

High

1045858

TF65
Transcription factor p65

1

11

High-throughput

0.479

High

1052917

HME1
Homeobox protein engrailed-1

1

3

High-throughput

0.479

High

1054804

SUH
Recombining binding protein suppressor of hairless

1

10

High-throughput

0.479

High

1056658

PAX8
Paired box protein Pax-8

1

11

High-throughput

0.479

High

1088069

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1091361

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.479

High

1102671

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

1106106

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

5

High-throughput

0.479

High

1133705

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1137559

SUZ12
Polycomb protein SUZ12

1

9

High-throughput

0.479

High

1140971

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1145845

IRF4
Interferon regulatory factor 4

1

2

High-throughput

0.479

High

1150010

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

1155846

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1160900

TBR1
T-box brain protein 1

1

12

High-throughput

0.479

High

1194430

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1276896

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

1295316

P66A
Transcriptional repressor p66-alpha

1

13

High-throughput

0.479

High

1308489

VRK3
Serine/threonine-protein kinase VRK3

1

6

High-throughput

0.479

High

1313491

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

1347280

OLIG1
Oligodendrocyte transcription factor 1

1

9

High-throughput

0.479

High

1351180

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

1367469

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1379960

LHX4
LIM/homeobox protein Lhx4

1

7

High-throughput

0.479

High

1401422

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1405448

FEV
Protein FEV

1

11

High-throughput

0.479

High

1413236

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1416670

SALL3
Sal-like protein 3

1

9

High-throughput

0.479

High

1416933

KLF16
Krueppel-like factor 16

1

12

High-throughput

0.479

High

1428658

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

4

High-throughput

0.479

High

1434979

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1438747

ZBT20
Zinc finger and BTB domain-containing protein 20

1

6

High-throughput

0.479

High

1448220

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

High-throughput

0.479

High

1452446

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

5

High-throughput

0.479

High

1453585

VSX1
Visual system homeobox 1

1

12

High-throughput

0.479

High

1454485

LHX3
LIM/homeobox protein Lhx3

1

7

High-throughput

0.479

High

1454486

ZMYM2
Zinc finger MYM-type protein 2

1

4

High-throughput

0.479

High

1454487

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1454488

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

1454490

ASF1A
Histone chaperone ASF1A

1

8

High-throughput

0.479

High

1454491

ZN330
Zinc finger protein 330

1

5

High-throughput

0.479

High

1454492

KLF12
Krueppel-like factor 12

1

18

High-throughput

0.479

High

1454493

ETV7
Transcription factor ETV7

1

13

High-throughput

0.479

High

1454489

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

911138

IMA1
Importin subunit alpha-1

1

20

High-throughput

0.445

High

911414

IMA5
Importin subunit alpha-5

1

20

High-throughput

0.445

High

1288387

TLK2
Serine/threonine-protein kinase tousled-like 2

1

4

Small-scale

0.445

High

1335397

CAMKV
CaM kinase-like vesicle-associated protein

1

1

High-throughput

0.445

High

1437385

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

1439289

E41L5
Band 4.1-like protein 5

1

8

High-throughput

0.445

High

1453269

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

859716

RL21
Large ribosomal subunit protein eL21

1

2

High-throughput

0.437

High

921819

COPB
Coatomer subunit beta

1

4

High-throughput

0.437

High

942935

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.437

High

1241973

FBX42
F-box only protein 42

1

3

High-throughput

0.437

High

886600

CTCF
Transcriptional repressor CTCF

1

5

Small-scale

0.408

High

1331436

MB213
Protein mab-21-like 3

1

7

High-throughput

0.407

High

914362

EFNA4
Ephrin-A4

1

0

High-throughput

0.249

Low

1068802

R51A2
RAD51-associated protein 2

1

0

High-throughput

0.249

Low

1352387

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025