Interactor 1: Q5BI50 (Q5BI50)
Cullin 4, isoform A (Cullin 4, isoform B) (FI05474p) (LP02965p)
Gene: Cul4
Interactor 2: RBX1A (Q9W5E1)
RING-box protein 1A (Regulator of cullins 1a) (dRbx1)
Gene: Roc1a
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18698375 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1 |
| Common GO terms | GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination GO:0045879 - negative regulation of smoothened signaling pathway GO:0080008 - Cul4-RING E3 ubiquitin ligase complex |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
