HitPredict

Interactor 1: LRC10 (Q5BKY1)
Leucine-rich repeat-containing protein 10
Gene: LRRC10

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 277 Hs			1 365
+	Hs
		1050095 SCRIB_HUMAN (5-277): 1.39e-57: 200: 22.19		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1301469 ERBIN_HUMAN (7-276): 9.04e-57: 197: 20.65		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1312326 LRRC1_HUMAN (1-223): 3.22e-44: 158: 26.46		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1023260 FLII_HUMAN (2-200): 3.5e-38: 144: 26.11		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1357816 SHOC2_HUMAN (6-186): 2.29e-36: 137: 30.22		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1294493 LRCH3_HUMAN (125-262): 9.02e-22: 96.7: 18.18		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73173 LRRC1_HUMAN (1-223): 3.22e-44: 158: 26.46		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		1334127 LRC40_HUMAN (34-157): 8.73e-20: 90.5: 36.00		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1155927 LRC8E_HUMAN (34-239): 2.3e-19: 89.5: 21.16		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73193 SHOC2_HUMAN (6-186): 2.29e-36: 137: 30.22		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73175 LRRC2_HUMAN (4-179): 3.52e-29: 115: 23.60		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73139 LRC10_HUMAN (1-154): 5.67e-23: 96.7: 20.78		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73168 LRCH3_HUMAN (125-262): 9.02e-22: 96.7: 18.18		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		858664 LRRC1_HUMAN (1-223): 3.22e-44: 158: 26.46		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		73181 LRC40_HUMAN (34-157): 8.73e-20: 90.5: 36.00		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73145 LRC8E_HUMAN (34-239): 2.3e-19: 89.5: 21.16		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		858616 FLII_HUMAN (2-200): 3.5e-38: 144: 26.11		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		73195 LRCH1_HUMAN (8-118): 1.5e-16: 81.4: 23.42		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		174879 SCRIB_HUMAN (5-277): 1.39e-57: 200: 22.19		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		175307 SHOC2_HUMAN (6-186): 2.29e-36: 137: 30.22		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51